全球滚环扩增市场 – 行业趋势和 2030 年预测

滚环扩增市场分析和规模

环境污染物是全球关注的问题，开发一种快速、现场且经济高效的监测方法是一种有效的补救策略。然而，这仍然很困难，特别是在检测复杂水环境中的各种污染物时。例如，分子方法的使用最近越来越流行，滚环扩增 (RCA) 是一种等温酶促过程，它使用环状模板和特殊的核酸聚合酶来扩增短核酸引物以形成长单链核酸。这种方法也可以开发成一种用于即时监测环境污染物的装置。

Data Bridge Market Research 分析，滚环扩增市场在 2022 年为 8.3475 亿美元，预计到 2030 年将达到 19.657 亿美元，在 2023 年至 2030 年的预测期内复合年增长率为 11.3%。除了对市场价值、增长率、细分、地理覆盖范围和主要参与者等市场情景的见解外，Data Bridge Market Research 策划的市场报告还包括深度专家分析、患者流行病学、管道分析、定价分析和监管框架。

滚环扩增市场范围和细分  

Market Definition

Rolling circle amplification (RCA) is an isothermal enzymatic process that uses a circular DNA template and special DNA or RNA polymerases to amplify a short DNA or RNA primer to form a long single stranded DNA or RNA. The RCA product is a concatemer composed of tens to hundreds of tandem repeats that complement the circular template. The DNA amplification technique's power, simplicity, and versatility have made it an appealing tool for biomedical research and nanobiotechnology. RCA has traditionally been used to create sensitive diagnostic methods for a wide range of targets such as nucleic acids (DNA, RNA), small molecules, proteins, and cells. RCA has also received a great deal of attention in the fields of nanotechnology and nanobiotechnology.

Rolling Circle Amplification Market Dynamics

Drivers

• Improve the accuracy of in-situ analysis

In commonly used RCA-based methods, rolling circle amplification (RCA) is used to generate distinct fluorescent signals in situ by relying on the self-collapsing properties of single-stranded DNA. The reduced size of RCPs increases the local concentration of fluorophores, increasing signal intensity and signal-to-noise ratio. Furthermore, we discovered that RCPs sometimes disintegrate and are recorded as multiple RCPs, which our cross-hybridizing DNA oligonucleotide prevents. These effects of RCP compaction improve the accuracy of both visual and automated in situ analysis for RCA-based methods such as proximity ligation assays (PLA) and padlock probes.

• Rising applications of rolling circle amplification

Immuno-RCA employs an antibody conjugated to an oligonucleotide to detect a single protein. A circular DNA template can be hybridized to this and then amplified by the enzyme phi29 polymerase with the antibody-conjugated oligonucleotide as a primer. This will result in the formation of an RCP that is covalently linked to the antibody. Two antibodies are conjugated with two different oligonucleotides in PLA (proximity probes). Suppose the proximity probes bind to their targets in close proximity. In that case, they will act as a hybridization/ligation template for two more oligonucleotides, resulting in the formation of a circular DNA template that can be amplified using one of the proximity probes as a primer for RCA.

Opportunities

• Increasing with the advancement of science and technology

Rolling circle amplification has been steadily increasing with the advancement of science and technology, which is expected to significantly impact cell rolling circle amplification during the forecast period of 2023 to 2030. Some of the factors that will drive the growth of the rolling circle amplification market include increased use to study and develop sensitive detection methods, which will allow for more efficient treatment and a higher survival rate for cancer patients, as well as advancements in the use of the RCA technique for biomedical applications and medical biosensors.

Restraints/Challenges

• High cost associated with synthesis

There are still some errors in the RCA method's development, the padlock probe is frequently close to 100 bp, the synthesis cost is relatively high. Also there is a problem with background interference during signal detection.

This rolling circle amplification market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the rolling circle amplification market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Global Rolling Circle Amplification Market Scope

The rolling circle amplification market is segmented on the basis of type, usage, application and end-user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Type

• Enzyme-Aided RCA Biosensor
• AuNP-RCA Biosensor
• Aptamer Biosensor
• Micromolecular Biosensor
• Transcription Factor (TF) Biosensor
• MiRNAs Biosensor
• Protein Biosensor
• Other

 Usage

• 分子生物学
• 材料科学
• 药品

 应用

• 诊断
• 基因组学
• 蛋白质组学
• 生物传感
• 药物研发
• 纳米技术

 终端用户

• 医院
• 研究机构
• 其他的

滚环扩增市场区域分析/见解

对滚环扩增市场进行了分析，并按国家、类型、用途、应用和最终用户提供了市场规模洞察和趋势。

滚动圆放大市场报告涵盖的国家包括北美洲的美国、加拿大和墨西哥、欧洲的德国、法国、英国、荷兰、瑞士、比利时、俄罗斯、意大利、西班牙、土耳其、欧洲其他地区、亚太地区 (APAC) 的中国、日本、印度、韩国、新加坡、马来西亚、澳大利亚、泰国、印度尼西亚、菲律宾、亚太地区 (APAC) 的其他地区、中东和非洲 (MEA) 的其他地区、南美洲的巴西、阿根廷和南美洲其他地区。

由于对医疗保健基础设施的高投入、政府资金的充足、技术进步以及基因检测领域的研究不断增加，北美在滚环扩增市场占据主导地位。

由于政府对医疗基础设施发展的优惠举措以及印度和中国等经济体的崛起，预计亚太地区将在 2023 年至 2030 年的预测期内实现最高增长率。

报告的国家部分还提供了影响单个市场因素和国内市场监管变化，这些因素和变化会影响市场的当前和未来趋势。下游和上游价值链分析、技术趋势和波特五力分析、案例研究等数据点是用于预测单个国家市场情景的一些指标。此外，在提供国家数据的预测分析时，还考虑了全球品牌的存在和可用性以及它们因来自本地和国内品牌的激烈或稀缺竞争而面临的挑战、国内关税和贸易路线的影响。

医疗保健基础设施增长安装基础和新技术渗透

滚动环扩增市场还为您提供每个国家/地区资本设备医疗支出增长、滚动环扩增市场不同类型产品的安装基数、使用生命线曲线的技术的影响以及医疗监管情景的变化及其对滚动环扩增市场的影响的详细市场分析。数据适用于 2011-2021 年的历史时期。

竞争格局和滚环放大市场份额分析

滚环扩增市场竞争格局按竞争对手提供详细信息。详细信息包括公司概况、公司财务状况、产生的收入、市场潜力、研发投资、新市场计划、全球影响力、生产基地和设施、生产能力、公司优势和劣势、产品发布、产品宽度和广度、应用主导地位。以上提供的数据点仅与公司对滚环扩增市场的关注有关。

滚环扩增市场的一些主要参与者是：

• 赛默飞世尔科技公司（美国）
• 雅培（美国）
• QIAGEN（德国）
• 安捷伦科技公司（美国）
• 拜耳公司（德国）
• BD（美国）
• F. Hoffmann-La Roche Ltd（瑞士）
• 生物梅里埃（法国）
• Bio-Rad Laboratories Inc.（美国）
• Takara Bio, Inc.（日本）

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