Pharmaceutical excipients are inert substances essential for drug formulation alongside active pharmaceutical ingredients (APIs). They perform critical roles such as enhancing stability, improving solubility, and controlling drug release. One pivotal application of excipients is in the development of controlled-release drug delivery systems. By modulating the release kinetics of APIs, excipients enable sustained or targeted delivery, which is crucial for managing chronic conditions effectively. This approach not only enhances therapeutic efficacy but also improves patient compliance by reducing dosing frequency and minimizing side effects, thereby optimizing overall treatment outcomes.
Global Pharmaceutical Excipients Market is expected to reach USD 12,199.90 million by 2029, with a growing CAGR of 6.6% during the forecast period 2022 to 2029.
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Below are the Top Pharmaceutical Excipients Companies with a Significant Market Share:
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Rank
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Company
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Overview
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Product Portfolio
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Sales Geographical Coverage
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Developments
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1.
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Dow
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Dow is a major player in the pharmaceutical excipients market, offering a wide range of excipients such as cellulose ethers, polymers, and solubility enhancers. They focus on innovation and sustainability, aiming to provide excipients that enhance drug delivery efficiency and patient safety.
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Americas, Middle East and Africa, Asia-Pacific, and Europe
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In September 2022, Dow launched DOWSIL Immersion Cooling Technology, a next-generation solution for cooling hyper-scale cloud and enterprise data centers with optimized efficiency and sustainability. It offers a revolutionary approach to thermal management and sustainability for fast-growing data centers in a new era of high-speed, high-volume data communications. This has helped the company to expand its product portfolio.
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2.
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Roquette Frères
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Roquette is known for its expertise in natural-based excipients derived from starch and other renewable sources. They offer solutions for controlled release, binding, and solubility enhancement in pharmaceutical formulations, catering to the growing demand for natural and organic excipients.
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Americas, Asia-Pacific, and Europe
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In December 2017, Roquette Frères partnered with Itacel, a leading player in the pharmaceutical excipients market in Brazil and Latin America. This has offered Roquette excipient for oral dosages in pharmaceutical and nutraceutical applications. This has helped the company to expand its business.
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3.
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Evonik Industries AG
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Evonik supplies a variety of functional excipients, including amino acids, surfactants, and lipid-based excipients. They emphasize advanced technologies to develop excipients that improve drug stability, bioavailability, and patient compliance, addressing the complex formulation challenges in the pharmaceutical industry.
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Americas, Middle East and Africa, Asia-Pacific, and Europe
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In May 2021, Evonik launched the EUDRACAP platform of easy-to-handle capsules to help the pharmaceutical industry accelerate the speed to market for complex oral drug products in early development stages. EUDRACAP enteric is the first product of the platform to become commercially available. This enteric-coated pre-locked capsule gives pharmaceutical companies access to a capsule that can optimize gastric resistance, boost intestinal absorption, and enhance bioavailability. This has helped the company to increase its revenue.
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4.
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The Lubrizol Corporation
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Lubrizol specializes in polymer-based excipients that enhance the performance and stability of pharmaceutical formulations. They offer excipients for modified release, taste masking, and bioavailability enhancement, focusing on providing solutions that meet stringent regulatory requirements and customer needs.
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Americas, Asia-Pacific, and Europe
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Lubrizol has been focusing on leveraging innovative excipients to support oral solid dosage innovation. For instance, the company's Carbopol 71G excipient has been used to develop high-dose, extended-release metformin tablets that exhibit improved drug loading and reduced tablet sizes.
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5.
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BASF SE
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BASF is a leading supplier of excipients, including polymers, solubilizers, and coatings for pharmaceutical applications. They focus on developing excipients that optimize drug delivery systems, improve drug bioavailability, and ensure product safety and efficacy, thereby supporting pharmaceutical companies in delivering innovative therapies to patients worldwide.
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North America, Asia-Pacific, and Europe
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In November 2017, BASF SE agreed with DIEM labs, LLC, to distribute the U.S. medical food product. This agreement has expanded the product portfolio of the company.
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Conclusion
In the dynamic pharmaceutical excipients market, companies such as Dow, Roquette Frères, Evonik Industries AG, The Lubrizol Corporation, and BASF SE play crucial roles by offering diverse and innovative solutions. Their contributions span from natural-based and polymer excipients to advanced technologies enhancing drug stability, bioavailability, and patient compliance. With a focus on sustainability, regulatory compliance, and meeting evolving industry demands, these companies drive the development of safer, more effective pharmaceutical formulations. Their ongoing research and commitment to excellence ensure they remain pivotal in supporting pharmaceutical companies worldwide in delivering high-quality therapies to patients.
