Combination therapies involving natural killer (NK) cell therapies require strategically integrating these immune cells with other treatment modalities such as chemotherapy, radiation therapy, or other immunotherapies to synergistically enhance overall treatment effectiveness. By combining NK cell therapies with traditional treatments, such as chemotherapy or radiation, the goal is to create a more potent and comprehensive attack on cancer cells. Additionally, pairing NK cell therapies with other immunotherapies or targeted therapies aims to address various aspects of cancer development and overcome potential resistance.
According to Data Bridge Market Research, the Global Natural Killer (NK) Cell Therapeutics Market will grow at a CAGR of 43.1% during the forecast period of 2023 to 2030.
"Immunotherapies awareness boosts the market growth"
The global natural killer (NK) Cell therapeutics market is being driven by a heightened awareness of immunotherapies, particularly NK cell therapies, as an essential approach for treating various malignancies. With cancer's devastating impact and concerns about the recurrence of tumors with existing treatments, there is a growing demand for more effective therapeutic options. While CAR-T cell therapies have been explored, their limitations have spurred the development of NK cell therapies. Despite the absence of approved NK cell therapeutic drugs, the increasing awareness of their potential benefits is influencing the market.
What restraints the growth of the global natural killer (NK) cell therapeutics market?
“Poor in-vivo survival of administered NK cells hampers the market growth”
A significant constraint in the global natural killer (NK) cell therapeutics market is the poor in-vivo survival of administered NK cells. Despite their crucial role in immune response, NK cells face challenges in maintaining prolonged effectiveness within the body due to factors such as the immunosuppressive microenvironment and interactions with other immune cells. This limitation hinders manufacturers from optimizing the sustained therapeutic impact of NK cell treatments, impacting their ability to persistently target and eliminate abnormal cells over time.
Segmentation: Global Natural Killer (NK) Cell Therapeutics Market
The global natural killer (NK) cell therapeutics market is segmented on the basis of therapeutics, approaches, application, end-user, and distribution channel.
- On the basis of therapeutics, the global natural killer (NK) cell therapeutics market is segmented into NK cell therapies and NK cell directed antibodies
- On the basis of approaches, the global natural killer (NK) cell therapeutics market is segmented into antibody-dependent cell-mediated cytotoxicity (ADCC) and bispecific antibodies
- On the basis of application, the global natural killer (NK) cell therapeutics market is segmented into cancer, immunoproliferative disorders, acute infectious diseases, gastrointestinal diseases, and others
- On the basis of end-user, the global natural killer (NK) cell therapeutics market is segmented into research and academic institutes, hospitals, and specialty clinics
- On the basis of distribution channel, the global natural killer (NK) cell therapeutics market is segmented into hospital pharmacies, direct tender, and others
Regional Insights: North America dominates the Global Natural Killer (NK) Cell Therapeutics Market
In North America, the U.S., dominates the pharmaceutical and biotechnology industry due to its large consumer market, high GDP, and technological leadership. The region's economic strength allows for significant investments in research and development, while its advanced technological environment fosters innovation in drug discovery and manufacturing. The U.S., with a stable regulatory framework and a culture of collaboration, serves as a global hub for industry leaders to expand their presence.
In Europe, the U.K. dominates the pharmaceutical and biotechnology sector due to its advanced technological capabilities, mass production of innovative therapeutics, and ability to meet the rising demand from emerging markets. The country's strong infrastructure, skilled workforce, and collaborative ecosystem position it as a key player in shaping the European pharmaceutical landscape.
In the Asia-Pacific, China's dominant healthcare sector is fueled by a heightened awareness of regular health check-ups. The country's proactive approach to preventive healthcare, government initiatives, and investments in advanced medical technologies have led to increased demand for healthcare services. China's large and health-conscious population has positioned it as a regional leader, influencing advancements in medical technology and healthcare delivery in the Asia-Pacific region.
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Recent Developments in the Global Natural Killer (NK) Cell Therapeutics Market
- In January 2022, Takeda bolstered its research and development efforts by acquiring Adaptate Biotherapeutics, gaining access to their innovative gamma delta (γδ) T cell engager platform. This strategic move allows Takeda to advance the development of novel therapies targeting solid tumors. The acquired platform includes Adaptate's pre-clinical candidate and discovery pipeline programs, featuring antibody-based γδ T cell engagers designed to selectively modulate immune responses at tumor sites while minimizing damage to healthy cells. This acquisition aligns with Takeda's commitment to advancing scientific innovation and further strengthens its focus on research and development
- In December 2021, Nektar Therapeutics demonstrated progress in its research and development initiatives with the announcement of phase 1b data for NKTR-358 (LY3471851). This novel T regulatory cell stimulator is designed to address autoimmune and inflammatory conditions by correcting immune system imbalances, particularly targeting increased levels of inflammatory T cells and compromised immune regulating Treg cells. The positive phase 1b results signify a significant advancement in Nektar Therapeutics' commitment to developing innovative solutions for treating atopic dermatitis and other related conditions, reinforcing the company's dedication to ongoing research and development efforts
The Prominent Key Players Operating in the Global Natural Killer (NK) Cell Therapeutics Market Include:
- Merck KGaA (Germany)
- BristolMyers Squibb Company (U.S.)
- Glycostem (Netherlands)
- Sanofi (France)
- Cytovia Therapeutics (U.S.)
- ImmunityBio, Inc. (U.S.)
- Biohaven Pharmaceuticals (U.S.)
- Fate Therapeutics (U.S.)
- EMERcell (South Korea)
- Phio Pharmaceuticals (U.S.)
- PersonGen BioTherapeutics (China)
- Innate Pharma (France)
- INmuneBIO (U.S.)
- Gamida Cell Israel
- Acepodia Inc. (U.S.)
- Affimed GmbH (Germany)
- Multimmune GmbH (Germany)
- iCell Gene Therapeutics (China)
- Takeda Pharmaceutical Company Limited (Japan)
- Regeneron Pharmaceuticals Inc (U.S.)
Above are the key players covered in the report, to know about more and exhaustive list of global natural killer (NK) cell therapeutics market companies contact, https://www.databridgemarketresearch.com/zh/contact
Research Methodology: Global Natural Killer (NK) Cell Therapeutics Market
Data collection and base year analysis are done using data collection modules with large sample sizes. The market data is analyzed and estimated using market statistical and coherent models. In addition, market share analysis and key trend analysis are the major success factors in the market report. The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market, and primary (industry expert) validation. Apart from this, data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Company Market Share Analysis, Standards of Measurement, global vs Regional and Vendor Share Analysis. Please request analyst call in case of further inquiry.
