Gene synthesis, a key aspect of synthetic biology, involves creating artificial genes in the laboratory. It is increasingly used in the production of recombinant proteins, a vital application of recombinant DNA technology. De novo gene synthesis is replacing traditional cloning and mutagenesis methods, allowing the production of nucleic acids without the need for a template. This technique revolutionizes genetic research and applications by enabling the creation of customized DNA sequences and accelerating scientific advancements.
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Data Bridge Market Research analyses that the Gene Synthesis Market is growing with a CAGR of 22.9% in the forecast period of 2022 to 2029 and is expected to reach USD 9,121.31 million by 2029 from USD 1,726.26 million in 2021. The rapid progress in DNA sequencing technologies, such as next-generation sequencing (NGS), and gene editing tools like CRISPR-Cas9 have significantly enhanced our ability to understand and manipulate genetic information. These advancements have increased the demand for gene synthesis services to create custom-designed DNA sequences for research, therapeutic, and industrial applications.
Key Findings of the Study
Growing focus on synthetic biology is expected to drive the market's growth rate
Synthetic biology focuses on creating artificial biological systems and components that are not found in nature. Gene synthesis plays a pivotal role in synthetic biology by allowing scientists to construct custom DNA sequences and genetic circuits. This capability enables the design and development of novel organisms, metabolic pathways, and biomolecules for various applications such as biofuel production, drug synthesis, and environmental remediation. The increasing interest and investment in synthetic biology are driving the demand for gene synthesis services, leading to the expansion of the gene synthesis market.
Report Scope and Market Segmentation
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Report Metric
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Details
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Forecast Period
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2022 to 2029
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Base Year
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2021
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Historic Years
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2020 (Customizable to 2014-2019)
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Quantitative Units
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Revenue in USD Million, Volumes in Units, Pricing in USD
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Segments Covered
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Component (Synthesizer, Consumables, and Software and Services), Gene Type (Standard Gene, Express Gene, Complex Gene and Others), Gene Synthesis Type (Gene Library Synthesis, and Custom Gene Synthesis), Application (Synthetic Biology, Genetic Engineering, Vaccine Design, Therapeutics Antibodies, and Others), Method (Solid Phase Synthesis, Chip-Based DNA Synthesis, and PCR-Based Enzyme Synthesis), End User (Academic and Research Institutes, Diagnostics Laboratories, Biotech and Pharmaceutical Companies, and Others), Distribution Channel (Direct Tender, Online Distribution, and Third Party Distributors)
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Countries Covered
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U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
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Market Players Covered
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ATDBio Ltd (Subsidiary of Biotage) (U.K.), General Biosystems, Inc. (U.S.), MACROGEN CO., LTD.(South Korea), Boster Biological Technology (U.S.), Creative Biogene (U.S.), Bioneer Pacific (South Korea), exonbio (U.S.), trenzyme GmbH (Germany), Twist Bioscience (U.S.), BioCat GmbH (Subsidiary of AddLife AB) (Germany), OriGene Technologies, Inc. (U.S.), Integrated DNA Technologies, Inc. (Subsidiary of Danaher Corporation) (U.S.), Eurofins Scientific(Luxembourg),NZYTech, Lda. - Genes and Enzymes (Portugal), Ansa Biotechnologies, Inc. (U.S.), Thermo Fisher Scientific (U.S.), Genescript (U.S.), Synbio Technologies (U.S.), Proteogenix (France), Bio Basic Inc (Canada), ATG biosynthetics GmbH(Germany), Merck KGaA: Germany (Germany), Kaneka Eurogentec S.A(Belgium), Ginkgo Bioworks (U.S.), Bbi-lifesciences (U.K.), Evonetix (U.K.), ProMab Biotechnologies, Inc. (U.S.), GCC Biotech (INDIA) Pvt. Ltd.(India), CSBio (U.S.), Azenta US, Inc.(U.S.) among others
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Data Points Covered in the Report
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In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.
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Segment Analysis:
The gene synthesis market is segmented on the basis of component, gene type, gene synthesis type, application, method, end user, and distribution channel
- On the basis of component, the global gene synthesis market is segmented into software and services, consumables, and synthesizer. The software and services segment is expected to dominate the market with a CAGR of 27.2% in the forecast period of 2022-2029 due to its vital role in maximizing the performance, usability, and efficiency of industrial display systems.
In 2022, the software and services segment is expected to dominate the product and service segment of the market
In 2022, the software and services segment is expected to dominate the product and service segment of the market owing to the display control, content management, remote monitoring, and other functionalities, as well as services such as installation, integration, training, and technical support with a CAGR of 27.2% in the forecast period of 2022-2029
- On the basis of gene synthesis type, the global gene synthesis market is segmented into custom gene synthesis and gene library synthesis. The custom gene synthesis segment is expected to dominate the market with a CAGR of 27.2% in the forecast period of 2022-2029 due to the demand for tailored DNA sequences and the ability to design and obtain genes with precise specifications.
- On the basis of application, the global gene synthesis market is segmented into synthetic biology, genetic engineering, therapeutic antibodies, vaccine design, and others. The synthetic biology segment is expected to dominate the market with a CAGR of 27.5% in the forecast period of 2022-2029 due to its potential to address challenges in various industries and its ability to enable the development of novel biological solutions.
- On the basis of method, the global gene synthesis market is segmented into PCR based enzyme synthesis, CHIP based DNA synthesis, and solid phase synthesis. PCR based enzyme synthesis segment is expected to dominate the market with a CAGR of 27.4% in the forecast period of 2022-2029 due to the miniaturized and parallel format. Additionally, it is frequently used in procedures like DNA sequencing, genotyping, and gene expression analysis.
- On the basis of end user, the global gene synthesis market is segmented into academic and research institutes, biotech and pharmaceutical companies, diagnostic laboratories, and other. Academic and research institutes segment is expected to dominate the market with a CAGR of 27.3% in the forecast period of 2022-2029 due to crucial role in advancing scientific knowledge and innovation
In 2022, the academic and research institutes segment is expected to dominate the end user segment of the market
In 2022, the academic and research institutes segment is expected to dominate the end user segment of the market owing to the revenue, they are vital for driving discoveries and advancements across industries. Their primary focus is on knowledge creation, and they contribute to the development of new technologies, methodologies, and scientific understanding, which can be further translated into commercial applications with a CAGR of 27.3% in the forecast period of 2022-2029
- On the basis of distribution channel, the global gene synthesis market is segmented into direct tender, online distribution and third party distributors. The direct tenders segment is expected to dominate the market with a CAGR of 27.4% in the forecast period of 2022-2029 due to its products directly to the end customers without involving intermediaries
Major Players
Data Bridge Market Research recognizes the following companies as the major gene synthesis market players in gene synthesis market are ATDBio Ltd (Subsidiary of Biotage) (U.K.), General Biosystems, Inc. (U.S.), MACROGEN CO., LTD.(South Korea), Boster Biological Technology (U.S.), Creative Biogene (U.S.), Bioneer Pacific (South Korea)
Market Development
- In 2020, Worldwide, an estimated 19.3 million new cases of cancer and nearly 10.0 million cancer deaths were reported, according to a study published in an ACS journal. This suggests that cancer coverage is not at its best, and there is a pressing need to increase cancer coverage globally.
- In 2020, Clonal-ready gene fragments were released by Twist Bioscience to complete the gene offering. To create the ideal clones, the fragments launched can be used with or without adapters. The clonal-ready gene fragments work with a variety of processes, including gene expression, enzyme engineering, and protein expression pathways.
- In 2020, Twist Bioscience launched clonal ready gene fragments to complete the offering of genes. The fragments launched can be used with adapters or without adapters to build up the perfect clones. The clonal ready gene fragments are compatible with the protein expression pathways, enzyme engineering, and gene expression among others
- In 2019, Codex DNA, Inc. (a Subsidiary of Synthetic Genomics Inc.) launched MTAC application for leveraging the Gibson Assembly technology to boost antibody and protein engineering. The product launched improved and enhanced the working efficiency of BioXp Gene Builder
- In 2019, Aldevron launched new GMP gene synthesis service for supporting the neo-antigen based oncology research activities among other applications. The service launched proved to be useful to researchers and scientists as it helped them to develop breakthrough therapies.
Regional Analysis
Geographically, the countries covered in the gene synthesis market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
As per Data Bridge Market Research analysis:
North America is the dominant region in gene synthesis market during the forecast period 2022-2029
North America maintains its dominant position in the gene synthesis market, both in terms of market share and revenue. The region's strong position is attributed to the increasing demand for verification and validation of gene synthesis processes, driven by rigorous quality standards and regulations. Furthermore, rapid research and development activities in the fields of genetics and genomics in North America contribute to the continued growth and flourishing dominance of the gene synthesis market in the region.
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