Latin America, North America, Africa and the Europe Osteosynthesis Devices market, By Product Type (Fixator Devices, Bone Growth Stimulators and Others), Material (Non-Degradable and Degradable), Fracture Type (Patella, Tibia and Fibula, Vertebral Column, Hip & Pelvis, Clavicle, Scapula, and Humerus, Femur, Radius or Ulna and Both, Wrist, Sternum, Ribs, Skull, and Facial Bones), Site (Lower Extremities and Upper Extremities), Patient Type (Adults, Geriatric, and Pediatric), End User (Hospitals, Orthopaedic Clinics, Ambulatory Surgical Centers, Trauma Centers, and Others), Distribution Channel (Direct Sales and Third Party Distributor) - Industry Trends and Forecast to 2031.
Latin America, North America, Africa and the Europe Osteosynthesis Devices Market Analysis and Size
Rising prevalence of osteoarthritis among the elderly population is expected to drive the market’s expansion in Latin America, North America, Africa and Europe. The Osteosynthesis Devices market is experiencing significant growth, driven by the rising trauma and fracture cases, rising prevalence of osteoarthritis among the elderly population, inclination towards minimally invasive osteosynthesis techniques, advancement in osteosynthesis devices and materials.
Latin America, North America, Africa and the Europe Osteosynthesis Devices market is expected to gain market growth in the forecast period of 2024 to 2031.
Data Bridge Market Research analyzes that the Latin America, North America, Africa and the Europe Osteosynthesis Devices market is growing with a CAGR of 7.9% in the forecast period of 2024 to 2031 and is expected to reach USD 7,435.11 million by 2031 from USD 4,026.67 million in 2023.
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Report Metric
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Details
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Forecast Period
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2024-2031
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Base Year
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2023
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Historic Year
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2022 (Customizable 2016-2021)
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Quantitative Units
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Revenue in USD Million
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Segments Covered
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Product Type (Fixator Devices, Bone Growth Stimulators, and Others), Material (Non-Degradable and Degradable), Fracture Type (Patella, Tibia and Fibula, Vertebral Column, Hip & Pelvis, Clavicle, Scapula, and Humerus, Femur, Radius or Ulna and Both, Wrist, Sternum, Ribs, Skull and Facial Bones), Site (Lower Extremities and Upper Extremities), Patient Type (Adults, Geriatric and Pediatric), End User (Hospitals, Orthopaedic Clinics, Ambulatory Surgical Centers, Trauma Centers and Others), Distribution Channel (Direct Sales and Third Party Distributor)
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Countries Covered
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U.S., Canada, Mexico, Germany, France, U.K., Italy, Spain, Russia, Netherlands, Switzerland, Turkey, Belgium, Denmark, Norway, Sweden, Poland, Rest of Europe, Brazil, Argentina, Colombia, Peru, Chile, EI Salvador, Panama, Honduras, Bolivia, Costa Rica, Ecuador, Guatemala, Paraguay, Jamaica, Trinidad and Tobago, Venezuela, Rep Dominicana, South Africa, Egypt, Algeria, Ghana, Kenya, Nigeria, Sudan, Uganda, Tanzania, Ethopia, Democratic Republic of Congo, rest of Africa
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Market Players Covered
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Smith & Nephew, Zimmer Biomet, Olympus Corporation, Lepu Medical Technology Co., Ltd., Precision Spine, Inc., MicroPort Scientific Corporation, B. Braun Medical Ltd, Stryker, Globus Medical, Medtronic, Arthrex Inc., Bioventus Inc., Exactech Inc., Normmed Medical, Medartis AG, Orthofix Medical Inc., and OssaTechnics among others
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Market Definition
Osteosynthesis devices are medical implants that act as the helping hand for broken bones, stabilizing and supporting them during the healing process. These devices, like plates and screws, intramedullary nails, and external fixators, come in various forms to fit the specific needs of the fracture and patient. By holding the bone fragments in the correct position, they allow new bone tissue to grow and fuse the broken pieces back into a solid bone.
The osteosynthesis devices market in Latin America, North America, Africa, and Europe represents a diverse and rapidly evolving sector within the global orthopedic industry. Osteosynthesis devices, including plates, screws, nails, and wires, are crucial in the surgical management of bone fractures and related conditions. In Latin America, the market is driven by increasing healthcare expenditure, a growing aging population, and a rising incidence of osteoporosis and osteoarthritis. Countries like Brazil and Mexico are leading in terms of market share due to advancements in healthcare infrastructure and a higher number of surgical procedures. The market's growth is further propelled by the adoption of innovative technologies and increasing awareness about advanced treatment options among healthcare professionals and patients. However, economic disparities and limited access to advanced medical facilities in some regions pose challenges to market expansion.
Latin America, North America, Africa and the Europe Osteosynthesis Devices Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:
Drivers
- Rising Trauma and Fracture Cases
Rising trauma and fracture cases significantly drive the osteosynthesis devices market across Latin America, North America, Africa, and Europe. The increasing incidence of road accidents, sports injuries, and falls, combined with an aging population prone to osteoporosis and fractures, fuels demand for advanced osteosynthesis devices. In these regions, the surge in surgical procedures to repair and stabilize broken bones necessitates the use of plates, screws, and intramedullary nails, thereby boosting market growth. Advancements in medical technology and a growing focus on improving patient outcomes further propel the adoption of these devices, making the osteosynthesis market a vital component of healthcare systems in these regions. The rise in trauma cases has led to a higher prevalence of fractures, which in turn increases the need for effective and reliable osteosynthesis solutions, driving innovation and investment in the market to meet the growing demand for these essential medical devices.
For instance,
- In August 2021, according to an article published in NCBI, a study was conducted on patients aged 0 years to 18 years, who were presented in the clinic between 21 March 2020 and 31 May 2020 (Group A1, n = 111), between 01 June 2020 and 31 August 2020 (Group A2, n = 214) and during the same periods in 2019 Group B1 (n = 220) and Group B2 (n = 211) were included. The prevalence of outdoor traumas (72.9% versus 61.1%), high-energy traumas (40.1% versus 26.5%), the rate of the patients treated with surgery (28% versus 17.1%) and the rate of admission to the emergency department (90.2% versus 58.3%) were significantly higher in Group A2 when compared with Group B2 (p < 0.05). The significant increase was observed in the number of outdoor injuries, high-energy traumas and fracture patterns that require surgical treatment
- In August 2021, according to an article published in the Lancet Healthy Longevity, a study was conducted to measure the global, regional, and national incidence, prevalence, and years lived with disability (YLDs) of fractures from 1990 to 2019. Globally, in 2019, there were 178 million (95% UI 162–196) new fractures (an increase of 33·4% [30·1–37·0] since 1990), 455 million (428–484) prevalent cases of acute or long-term symptoms of a fracture (an increase of 70·1% [67·5–72·5] since 1990), and 25·8 million (17·8–35·8) YLDs (an increase of 65·3% [62·4–68·0] since 1990). In 2019, age-specific rates of fracture incidence were highest in the oldest age groups, with, for instance, 15 381·5 incident cases (11 245·3–20 651·9) per 100 000 populations in those aged 95 years and older
- In April 2023, according to an article published in NCBI, a study was conducted to present the nationwide rates of hospitalized patients with vertebral fractures over one decade and to comprehensively analyze the treatment characteristics and direct costs incurred in 2019. Result showed that in total 955,091 fractures of the spine were registered between 2009 and 2019, with 70,235 recorded in 2009. The total number increased by 45.6% to 102,285 fractures in 2019, giving a change in the incidence rate from 105.8/100,000 inhabitants to 150.7/100,000 inhabitants
The rising number of trauma and fracture cases in Latin America, North America, Africa, and Europe is driving significant growth in the osteosynthesis devices market. Increased road accidents, sports injuries, and an aging population contribute to higher demand for surgical implants like plates, screws, and nails to stabilize fractures. Technological advancements and a focus on better patient outcomes further support this market expansion, making osteosynthesis devices a critical element of modern healthcare in these regions.
- Rising Prevalence of Osteoarthritis among the Elderly Population
The rising prevalence of osteoarthritis among the elderly population acts as a significant driver in the osteosynthesis devices market across Latin America, North America, Africa, and Europe. As the elderly population grows, the incidence of osteoarthritis—a degenerative joint disease that often leads to severe joint pain and mobility issues—also increases. This condition frequently necessitates surgical interventions such as joint replacement and bone realignment, which in turn require the use of osteosynthesis devices like plates, screws, and rods to stabilize and support the affected bones and joints. The surge in osteoarthritis cases leads to a higher demand for these surgical procedures, thereby boosting the market for osteosynthesis devices. Also, advancements in medical technology, improved surgical techniques, and a growing emphasis on enhancing the quality of life for elderly patients further drive the adoption of these devices. Consequently, the osteosynthesis devices market is experiencing substantial growth as healthcare systems in these regions strive to address the increasing needs of an aging population afflicted with osteoarthritis.
For instance,
- In July 2023, according to the new/facts published by WHO, in 2019, about 528 million people worldwide were living with osteoarthritis; an increase of 113% since 1990, About 73% of people living with osteoarthritis are older than 55 years, and 60% are female, with ageing populations and increasing rates of obesity and injury, the prevalence of osteoarthritis is expected to continue to increase globally. Osteoarthritis is not an evitable consequence of ageing. With a prevalence of 365 million, the knee is the most frequently affected joint, followed by the hip and the hand
- In November 2020, according to an article published in the eClinicalMedicine, a study was conducted to find that knee osteoarthritis (OA) is a major cause of disability in the elderly. Out of 9570 records identified, 88 studies with 10,081,952 participants were eligible for this study. The pooled global prevalence of knee OA was 16⋅0% in individuals aged 15 and over and was 22⋅9% in individuals aged 40 and over. Correspondingly, there are around 654⋅1 million individuals (40 years and older) with knee OA in 2020 worldwide. The pooled global incidence of knee OA was 203 per 10,000 person-years in individuals aged 20 and over. Correspondingly, there are around annual 86⋅7 million individuals (20 years and older) with incident knee OA in 2020 worldwide. This result showed that the prevalence of osteoarthritis is more among the elderly population which acts as a driver in the market growth
- In September 2021, according to an article published in NCBI, osteoarthritis (OA) incidence increased over time from 7.36 per 1000 persons in 2013 to 8.23 per 1000 persons in 2017 The incidence was lowest in patients under 60 years (in both sexes) and peaked at 60–70 years. In older ages, the incidence leveled off in men and declined in women. OA is likely to increase with an ageing population and an obesity pandemic
The increasing prevalence of osteoarthritis among the elderly in Latin America, North America, Africa, and Europe significantly boosts the osteosynthesis devices market. As more elderly individuals require surgical interventions like joint replacements and bone realignments due to severe joint pain and mobility issues, the demand for plates, screws, and rods rises. So rising prevalence of osteoarthritis among the elderly population act as a driver in the market growth.
Opportunity
- Increase Research and Development in Osteosynthesis Devices
Increasing Research and Development (R&D) in osteosynthesis devices presents significant opportunities for market growth by driving innovation and improving patient outcomes. The integration of digital technologies, such as 3D printing and AI-driven design, can enable the creation of customized implants tailored to individual patient anatomies, thereby improving the success rates of surgical interventions. Also, Enhanced R&D efforts can lead to the development of advanced materials, such as bioresorbable polymers and shape-memory alloys, which offer superior biocompatibility and mechanical properties. This can reduce complications and promote faster healing, making these devices more appealing to both surgeons and patients. Increased focus on minimally invasive techniques can also expand the market by reducing recovery times and hospital stays, making procedures more cost-effective and attractive to healthcare providers and payers. Robust R&D can facilitate the development of new product lines and enhancements, driving brand loyalty and competitive differentiation. Regulatory approvals gained through rigorous testing and clinical trials further instill confidence in the safety and efficacy of these devices, encouraging adoption across global markets. Overall, sustained investment in R&D not only fosters technological advancements but also strengthens market positioning, opening new revenue streams and ensuring long-term growth in the osteosynthesis device sector.
For instance,
- In June 2023, according to an article published in European Journal of Trauma and Emergency Surgery, study aimed to assess whether patient-specific osteosyntheses could facilitate proper fracture reduction in medial tibial plateau fractures. A 3D surgical plan was created and a patient-specific implant was designed and fabricated for each fracture. Drilling guides that fitted on top of the customized plates were designed and 3D prints in order to assist the surgeon in positioning the plate and steering the screws in the preplanned direction. Result shows that the development and implementation of a patient-specific workflow for medial tibial plateau fracture surgery facilitates proper fracture reduction
- In September 2021, according to an article published in Journal of Computational Design and Engineering, study aimed to reduce complications related to the osteosynthesis plating system, the use of a patient-specific plate design was proposed. Patient-specific plates have superior advantages as compared with conventional mini-plates, including accuracy, short operation time, and reasonable cost for the stability. The patient-specific design approach entailed structural designs that can be implemented for individual anatomies and does not require a preoperative bending procedure. Moreover, with the advances in additive manufacturing technology (e.g. 3D printing), the temporal and physical costs of reconstruction with patient-specific plates have decreased. Thus, patient-specific design approaches are being increasingly preferred as a treatment option
- In January 2019, according to an article published in NCBI, study is conducted to develop orthopedic implants that are optimized for each patient’s needs or skeletal structure (custom-made implants). Four-point bending tests and compression bending tests of osteosynthesis devices (bone plates, intramedullary nail rods, spinal rods, compression hip screws (CHSs), short femoral nails, and metaphyseal plates) were carried out to measure their bending stiffness, bending strength, and durability. Result showed that the bending strength, bending stiffness, and durability of various types of osteosynthesis devices (bone plates, intramedullary nail rods, spinal rods, CHSs, short femoral nails, and metaphyseal plates) were increased to promote the development of implants that are suitable for the skeletal structure of patients using 3D layer manufacturing technologies
Investing in research and development in osteosynthesis devices can significantly boost the market growth by driving technological innovation, improving patient outcomes, and expanding the range of advanced, customized, and minimally invasive products. These advancements leads to better biocompatibility, faster recovery, and cost-effectiveness, which increases adoption and brand loyalty while enhancing the market trust, opening new revenue opportunities and ensuring sustained growth in the sector.
Restraint/Challenge
- Complications Associated with Osteosynthesis Devices
Complications associated with osteosynthesis devices act as significant restraints in the market across Latin America, North America, Africa, and Europe by raising concerns about patient safety and long-term outcomes. Issues such as infection, implant failure, non-union or delayed union of fractures, and allergic reactions to implant materials can lead to prolonged hospital stays, additional surgeries, and increased healthcare costs. These potential complications create apprehension among patients and healthcare providers, impacting the adoption rate of osteosynthesis devices. Also, stringent regulatory requirements and the need for extensive clinical trials to ensure the safety and efficacy of new devices further slowdown market growth. The fear of legal liabilities and the high costs associated with managing complications also deter manufacturers from investing heavily in research and development. Consequently, these factors collectively hinder the expansion of the osteosynthesis devices market in these regions.
For instance,
- In March 2024, according to an article published in Journal of Clinical Medicine, a study was conducted to review clinical studies assessing the benefits and harms of fracture fixation with locked plates in AO/OTA Type 32 and 33 femur fractures. This aimed to systematically synthesize the available evidence on the risk associated with locked plating osteosynthesis in distal femur fractures. 53 studies with 1788 patients were found to satisfy the inclusion and exclusion criteria. The most common harms were nonunion (14.8%), malunion (13%), fixation failure (5.3%), infection (3.7%), and symptomatic implant (3.1%). Nonunion is the most common harm and is the primary cause of reoperation
- In August 2021, according to an article published in NCBI, a study was conducted to find implant removal associated complications after ESIN osteosynthesis in pediatric fractures, complication rate in 384 TEN removals was 3.1% (n = 12). One major complication (rupture of M. extensor pollicis brevis) was documented. One refracture at the forearm occurred, however, remodeling prior TEN removal was completed. Ten minor complications were temporary or without irreversible restrictions (3 infections, 5 scaring/granuloma, 2 temporary paresthesia). However, the complication rate is low but these complications are major and act as a restraint in the market growth
- In March 2020, according to an article published in materials journal, a study was conducted to evaluate the main causes for osteosynthesis implant breakdown and the relations among them for a series of cases. Twenty-one patients diagnosed with implant failure were assessed for this work. For metallurgical analysis, microscopy techniques such as scanning electron microscopy (SEM), stereomicroscopy, and optical microscopy were employed. The results showed that material structural deficiencies (nine patients) and faulty surgical techniques (eight patients) were the main causes for failure. An important number of patients presented with material structural deficiencies superimposed on an imperfect osteosynthesis technique (six patients)
- In September 2019, according to an article published in Journal of Orthopedic Surgery, proximal femur is one of the most frequent human injuries, and most of the patients are treated with osteosynthesis, such as intramedullary nails. These patients often require magnetic resonance imaging (MRI) scans in their further lives due to various reasons. There were no complications during the MRI scan, in the first 2 weeks after MRI but in long term some complications are common which is associated with wrong implants procedures
Complications like infections, implant failures, and allergic reactions significantly restrains the osteosynthesis devices market in Latin America, North America, Africa, and Europe. These issues raise patient safety concerns, leading to hesitation in adoption and increased healthcare costs. Strict regulations and the high cost of managing complications further slow market growth, deterring investment in new technologies and limiting market expansion.
Recent Developments
- In April, Smith & Nephew’s PICO Single Use Negative Pressure Wound Therapy System provided better clinical outcomes versus standard of care according to UK National Institute for Health and Care Excellence (NICE). As a result, NICE reconfirmed its guidance, that PICO sNPWT should be considered as an option for closed surgical incisions in patients who are at high risk of surgical site infections, remains the same. Key high-risk factors included high body mass index (BMI), diabetes, renal insufficiency and smoking among others
- In June, Sheffield-based Aesculap Academia UK was awarded a prestigious quality mark by the Royal College of Surgeons of England. The award is given in recognition of outstanding surgery-related education provision by Aesculap Academia and means that the company is now accredited as an official the Royal College of Surgeons of England centre for a further three years
- In September 2023, Globus Medical, Inc. a leading musculoskeletal solutions company, today announced it has completed its previously announced merger with NuVasive Inc. The combined company provided surgeons and patients with one of the most comprehensive offerings of musculoskeletal procedural solutions and enabled technologies to impact the care continuum
- In July 2023, Globus Medical, Inc. a leading musculoskeletal solutions company, today announced the commercial launch of the MARVEL Growing Rod System, which was designed for pediatric patients with early onset scoliosis to obtain and maintain correction while allowing for growth through minimally invasive distraction
- In June 2024, Stryker a global leader in medical technologies, announced the signing of a definitive agreement to acquire all the issued and outstanding shares of Artelon, a privately held company specializing in innovative soft tissue fixation products for foot and ankle and sports medicine procedures. The acquisition strengthened Stryker’s offerings in the soft tissue fixation segment and highlights Stryker’s commitment to providing differentiated solutions for ligament and tendon reconstruction
- In January, Zimmer Biomet announced that it had reached a definitive agreement to acquire Embody, Inc., a privately-held medical device company focused on soft tissue healing, for 155 million at closing. The acquisition includes Embody's complete portfolio of collagen-based biointegrative solutions to support healing in the most challenging orthopedic soft tissue injuries – including the TAPESTRY biointegrative implant for tendon healing and TAPESTRY RC, one of the first arthroscopic implant systems for rotator cuff repair. This acquisition helped the company in its product portfolio and business expansion
- In January, Arthrex a global leader in minimally invasive surgical technology and surgical skills education, launched a new patient-focused resource, TheNanoExperience.com, highlighted the science and benefits of Nano arthroscopy, a modern, least-invasive orthopedic procedure that may allow for a quick return to activity and less pain
- In January, Arthrex, a global leader in minimally invasive surgical technology, announced today its ACL TightRope implant has received clearance from the U.S. Food and Drug Administration (FDA) for pediatric indications. The TightRope implant is used in the surgical treatment of orthopedic injuries and is the first and only fixation device for anterior cruciate ligament (ACL) injuries cleared for pediatric use
- In October, Bioventus, a global leader in innovations for active healing, presented its comprehensive spine procedural solutions at the North American Spine Society (NASS) meeting in Chicago. This event marks the full launch of the BoneScalpel Access
- In February, Exactech forged a pioneering collaboration with Statera Medical to co-develop the world's inaugural smart reverse shoulder implant. This innovative partnership aimed to integrate advanced technology into orthopedic solutions, enhancing surgical precision and patient outcomes. By combining Exactech's expertise in joint replacement with Statera Medical's innovative approach to medical device development, the collaboration promised to redefine standards in shoulder surgery with enhanced functionality and patient-centric design
- In April, Medtronic plc a global leader in healthcare technology, today announced that the U.S. Food and Drug Administration (FDA) has approved the Inceptiv vclosed-loop rechargeable spinal cord stimulator (SCS) for the treatment of chronic pain. Inceptiv is the first Medtronic SCS device to offer a closed-loop feature that senses biological signals along the spinal cord and automatically adjusts stimulation in real time, keeping therapy in harmony with the motions of daily life
Latin America, North America, Africa and the Europe Osteosynthesis Devices Market Scope
Latin America, North America, Africa and the Europe Osteosynthesis Devices market is segmented into seven notable segments based on product type, material, fracture type, site, patient type, end user, and distribution channel.
Product Type
- Fixator devices
- Bone growth stimulators
- Others
On the basis of product type, the market is segmented into fixator devices, bone growth stimulators, and others.
Material
- Non-degradable
- Degradable
On the basis of material, the market is segmented into non-degradable and degradable.
Fracture Type
- Patella, Tibia and Fibula
- Vertebral Column
- Hip & Pelvis
- Clavicle, Scapula, and Humerus
- Femur
- Radius or Ulna and Both
- Wrist
- Sternum
- Ribs
- Skull
- Facial Bones
On the basis of fracture type, the market is segmented into patella, tibia and fibula, vertebral column, hip & pelvis, clavicle, scapula, and humerus, femur, radius or ulna and both, wrist, sternum, ribs, skull and facial bones.
Site
- Lower Extremities
- Upper Extremities
On the basis of site, the market is segmented into lower extremities and upper extremities.
Patient Type
- Adults
- Geriatric
- Pediatric
On the basis of patient type, the market is segmented into adults, geriatric and pediatric.
End User
- Hospitals
- Orthopedic clinics
- Ambulatory surgical centers
- Trauma centers
- others
On the basis of end user, the market is segmented into hospitals, orthopedic clinics, ambulatory surgical centers, trauma centers and others
Distribution Channel
- Direct sales
- Third party distributor
On the basis of distribution channel, Latin America, North America, Africa and the Europe osteosynthesis devices market is segmented into direct sales and third party distributor
Latin America, North America, Africa and the Europe Osteosynthesis Devices Market Regional Analysis/Insights
Latin America, North America, Africa and the Europe osteosynthesis devices market is analyzed and market size insights and trends are provided based on on product type, material, fracture type, site, patient type, end user, and distribution channel as referenced above.
The countries covered in this market report are U.S., Canada, Mexico, Germany, France, U.K., Italy, Spain, Russia, Netherlands, Switzerland, Turkey, Belgium, Denmark, Norway, Sweden, Poland, rest of Europe, Brazil, Argentina, Colombia, Peru, Chile, EI Salvador, Panama, Honduras, Bolivia, Costa Rica, Ecuador, Guatemala, Paraguay, Jamaica, Trinidad and Tobago, Venezuela, Rep Dominicana, South Africa, Egypt, Algeria, Ghana, Kenya, Nigeria, Sudan, Uganda, Tanzania, Ethopia, Democratic Republic of Congo, rest of Africa.
North America is expected to dominate the market due to its robust healthcare infrastructure, high healthcare spending, advanced technological adoption, and significant investments in orthopedic research and development.
The country section of the report also provides individual market-impacting factors and changes in market regulation that impact the current and future trends of the market. Data points such as downstream and upstream value chain analysis, technical trends, Porter's five forces analysis, and case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs, and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and Latin America, North America, Africa and the Europe Osteosynthesis Devices Market Share Analysis
Latin America, North America, Africa and the Europe Osteosynthesis Devices market competitive landscape provides details of competitors. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, Global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points provided are only related to the companies' focus on the Latin America, North America, Africa and the Europe Osteosynthesis Devices Market. Some of the major players operating in the Latin America, North America, Africa and the Europe Osteosynthesis Devices market are Smith & Nephew, Zimmer Biomet, Olympus Corporation, Lepu Medical Technology (Beijing) Co. Ltd., Precision Spine Inc., MicroPort Scientific Corporation, B. Braun Medical Ltd, Stryker, Globus Medical, Medtronic, Arthrex, Inc., Bioventus Inc., Exactech, Inc., Normmed Medical, Medartis AG, Orthofix Medical Inc., and OssaTechnics.
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