India Gene Synthesis Market, By Component (Synthesizer, Consumables, and Software & Services), Gene Type (Standard Gene, Express Gene, Complex Gene, and Others), Gene Synthesis Type (Gene Library Synthesis and Custom Gene Synthesis), Application (Synthetic Biology, Genetic Engineering, Vaccine Design, Therapeutic Antibodies, and Others), Method (PCR-Based Enzyme Synthesis, Chip-Based DNA Synthesis, and Solid Based Synthesis), End User, (Academic & Research Institutes, Diagnostic Laboratories, Biotech & Pharmaceutical Companies, Contract Research Organizations (CROs), Agriculture, Food, and Others), Distribution Channel (Direct Tender, Online Distributions, and Third Party Distributors) - Industry Trends and Forecast to 2030.
India Gene Synthesis Market Analysis and Insights
Bacterial and viral diseases are rapidly expanding due to the rising prevalence of infectious diseases, which is expected to increase the demand for novel and effective therapies against such deadly diseases. This disease can be cured using chemical drugs, and biological therapies including gene therapy.
The major factors responsible for the rapid development of gene synthesis are the increased prevalence of chronic infectious diseases, rising adoption of gene therapy, expansion of synthetic biology, and rising interest in gene synthesis in the field of molecular biology. The factors which are expected to restrain the market growth are a lack of trained professionals, ethical issues, and a long approval process. On the other hand, the rise in healthcare expenditure, strategic initiatives by market players, and increased interest in customized medications are expected to act as opportunities for the market.
The factors which are expected to challenge the market growth are technical limitations across the production process and the lack of a well-defined patent system. The dramatic rise in the quality of research coupled with increasing research opportunities is because of various strategic initiatives taken by key market players. They are taking initiatives such as product launches, collaborations, mergers, acquisitions, and many more over the years and are expected to lead and create more opportunities in the market.
Data Bridge Market Research analyzes that the market is expected to reach a value of USD 459.81 million by 2030, at a CAGR of 25.5% during the forecast period. Component accounts for the largest service type segment in the market due to product approval received improved workflow of sequencing and software and services which offer significant reductions in DNA synthesis cost due to their dense and massively parallel feature designs. This market report also covers pricing analysis, patent analysis, and technological advancements in depth.
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Report Metric
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Details
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Forecast Period
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2023 to 2030
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Base Year
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2022
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Historic Years
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2021 (Customizable to 2015 – 2020)
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Quantitative Units
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Revenue in USD Million, Volumes in Units, Pricing in USD
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Segments Covered
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Component (Synthesizer, Consumables, and Software & Services), Gene Type (Standard Gene, Express Gene, Complex Gene, and Others), Gene Synthesis Type (Gene Library Synthesis and Custom Gene Synthesis), Application (Synthetic Biology, Genetic Engineering, Vaccine Design, Therapeutic Antibodies, and Others), Method (PCR-Based Enzyme Synthesis, Chip-Based DNA Synthesis, and Solid Based Synthesis), End User, (Academic & Research Institutes, Diagnostic Laboratories, Biotech & Pharmaceutical Companies, Contract Research Organizations (CROs), Agriculture, Food, and Others), Distribution Channel (Direct Tender, Online Distributions, and Third Party Distributors)
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Country Covered
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India
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Market Players Covered
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The major companies which are dealing in the India gene synthesis market are Thermo Fisher Scientific Inc., Boster Biological Technology, Twist Bioscience, OriGene Technologies, Inc., Eurofins Scientific, GenScript, Merck KGaA, Kaneka Eurogentec S.A, Synbio Technologies, and GCC Biotech (INDIA) Pvt. Ltd. among others
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India Gene Synthesis Market Definition
Gene synthesis refers to the chemical synthesis of DNA strand base by base. Different DNA replication that occurs in cells or by Polymerase Chain Reaction (PCR), gene synthesis does not require a template strand. Rather, gene synthesis involves the step-wise addition of nucleotides to a single-stranded molecule, which then serves as a template for the creation of a complementary strand. Gene synthesis is the fundamental technology upon which the field of synthetic biology has been built.
The technological progressions in gene synthesis have modernized synthetic biology research. Scientists are no longer limited to classical methods of manipulating a single gene at a time; they now have the power to design or reprogram entire genomes and cells. The newly synthesized viral genomes are expected to boost vaccine development, eliminate cancer cells and produce sustainable biofuels, in the coming future. We can detect and break down environmental pollutants in the soil, air, and water. Biotechnology and life science researchers and academia across many research discipline areas are accelerating the advancements in healthcare, agriculture, energy, and other fields of human endeavor, through the use of newly synthesized genomes.
India Gene Synthesis Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:
Drivers
- Increased Prevalence of Chronic Infectious Diseases
Bacterial and viral diseases are rapidly expanding due to the rising prevalence of infectious diseases in the world. As a result, the demand for novel and effective therapies has increased to fight against such deadly diseases. These diseases can be cured by using chemical drugs and biological therapies, including gene therapy.
With a rising need for personalized treatments, drug development, vaccine research, and diagnostics tailored to the specific genetic characteristics of pathogens and individuals, gene synthesis becomes a pivotal tool. Investments in R&D and infrastructure are expected to increase as the Indian healthcare system and biotechnology sector pivot to tackle these diseases. This, in turn, is expected to drive market growth, offering novel avenues for the creation of targeted therapies, rapid vaccine development, precise diagnostics, and in-depth genetic research focused on chronic infectious diseases.
- Rising Adoption of Gene Therapy
Gene therapy is an advanced technique that includes the usage of several genes for the prevention of a particular disease type. The technique involves the insertion of genes into patient cells instead of drugs and surgery. The adoption of gene therapy is rising due to increased demand for novel and long-lasting therapy results. Gene therapies demand synthetic gene constructs, among other gene products, to accelerate gene therapy development. The demand for a proper cure is one major factor, and with the help of gene therapy, a particular disease type can be cured as there is a rise in genetic diseases.
The demand for custom-designed DNA sequences through gene synthesis becomes paramount as the understanding of genetics deepens and technological advancements enable more precise and effective gene therapies.
Lifesaving medicines and therapies are in huge demand to provide quality life to different kinds of patients. These rising numbers of patients are largely dependent upon the gene therapies available to achieve a proper cure. For the manufacturing of gene therapies, synthetic and novel genes are required, which can be achieved by the gene synthesis technique. Thus, the rising adoption of gene therapy is expected to drive market growth.
Opportunity
- Rise in Healthcare Expenditure
Healthcare expenditure has increased across the world as people's disposable income in various countries is increasing. Moreover, to accomplish the population requirements, government bodies, and healthcare organizations are taking the initiative under accelerating healthcare expenditure. The substantial rise in healthcare expenditure in India presents a significant opportunity for growth within the gene synthesis market. Gene synthesis stands out as a pivotal tool for advancing precision medicine and personalized treatments as the country allocates increasing resources to enhance its healthcare infrastructure and address a range of medical challenges. The heightened investment in healthcare translates into greater demand for innovative solutions that can effectively tackle complex diseases, including genetic and chronic conditions.
Growing healthcare expenditure is also beneficial for further economic growth and healthcare sector growth, and it is primarily fruitful as it significantly affects the development of better and more advanced medical products in the market. Thereby, the surge in healthcare expenditure is expected to create opportunities for market growth.
Restraints/Challenges
- Lack of Trained Professionals
Gene synthesis includes the use of advanced software, microchips, and services that require trained professionals having computational knowledge of genomics.
The growth of the gene synthesis market in India is probable to face constraints due to the current shortage of trained professionals in the field. Gene synthesis involves complex molecular biology techniques, bioinformatics analysis, and a deep understanding of genetic engineering principles. However, the number of skilled professionals equipped with the necessary expertise to design, validate, and execute gene synthesis projects is limited. This scarcity of trained personnel can lead to challenges in meeting the increasing demand for gene synthesis services.
The advancements in technology, and gene synthesis has resulted in increased demand for trained and skilled professionals. However, the lack of sufficient training modules and sessions restricts professionals and researchers from knowing the exact underlying principle and thus reduces the effectiveness of gene synthesis products and services, which is expected to restrain the market growth.
- Regulatory Framework
The regulatory landscape in India can pose significant challenges to the growth and operation of the market. Gene synthesis involves the creation of custom DNA sequences, which have diverse applications ranging from biotechnology research to medical treatments. However, the dynamic nature of this field, coupled with the potential biosecurity and ethical concerns surrounding gene synthesis, has led to the development of intricate regulatory frameworks.
Striking the right balance between encouraging technological advancement and ensuring ethical and environmental safeguards is challenging. Regulatory bodies need to consider both the potential benefits and risks associated with gene synthesis, which may slow down decision-making processes and limit the scope of research in certain areas. In addition, differing regulations across regions and countries can impact cross-border collaborations and trade in gene synthesis services, which is expected to pose a challenge to market growth.
Recent Developments
- In August 2022, Thermo Fisher Scientific Inc. announced that they had launched Applied Biosystems HIV-1 Genotyping Kit with Integrase, which will help to examine positive samples of the human immunodeficiency virus (HIV) to identify genetic variants that resist common antiretroviral therapeutics.
- In February 2022, Kaneka Eurogentec announced that its mRNA manufacturing facility has successfully produced a 25 g batch of mRNA for a US customer. This quantity is equivalent to 100,000’s to millions of doses of mRNA, potentially sufficient for late clinical and commercial uses.
- In September 2021, Eurofins Scientific Collaborate with Transplant Genomics to launch omnigraf , the only combination biomarker panel that provides the earliest indication of rejection in kidney transplant recipients as it provides significantly higher positive predictive value (PPV) and negative predictive value (NPV) than any other kidney rejection assays (or tests) on the market.
- In December 2020, Twist Bioscience launched clonal-ready gene fragments to complete the offering of genes. The fragments launched can be used with adapters or without adapters to build up the perfect clones. The clonal-ready gene fragments are compatible with the protein expression pathways, enzyme engineering, and gene expression among others.
India Gene Synthesis Market Scope
India gene synthesis market is segmented into component, gene type, gene synthesis type, application, method, end user, and distribution channel. The growth among segments helps you analyze niche pockets of growth and strategies to approach the market and determine your core application areas and the difference in your target markets.
Component
- Synthesizer
- Consumables
- Software & Services
On the basis of component, the market is segmented into synthesizer, consumables, and software & services.
Gene Type
- Standard Gene
- Express Gene
- Complex Gene
- Others
On the basis of gene type, the market is segmented into standard gene, express gene, complex gene, and others.
Gene Synthesis Type
- Gene Library Synthesis
- Custom Gene Synthesis
On the basis of gene synthesis type, the market is segmented into gene library synthesis and custom gene synthesis.
Application
- Synthetic Biology
- Genetic Engineering
- Vaccine Design
- Therapeutic Antibodies
- Others
On the basis of application, the market is segmented into synthetic biology, genetic engineering, vaccine design, therapeutic antibodies, and others.
Method
- Solid Phase Synthesis
- Chip-Based DNA Synthesis
- PCR-Based Enzyme Synthesis
On the basis of method, the market is segmented into solid phase synthesis, chip-based DNA synthesis and PCR-based enzyme synthesis.
End User
- Academic & Research Institutes
- Diagnostic Laboratories
- Biotech & Pharmaceutical Companies
- Contract Research Organizations (CROs)
- Agriculture
- Food
- Others
On the basis of end user, the market is segmented into academic & research institutes, diagnostic laboratories, biotech & pharmaceutical companies, contract research organizations (CROs), agriculture, food and others.
Distribution Channel
- Direct Tender
- Online Distribution
- Third Party Distributors
On the basis of distribution channel, the market is segmented into direct tender, online distribution, and third party distributors.
Competitive Landscape and India Gene Synthesis Market Share Analysis
India gene synthesis market competitive landscape provides details of competitors. Details included are company overview, company financials, revenue generated, market potential, investment in R&D, new market initiatives, production sites and facilities, company strengths and weaknesses, product launch, product trials pipelines, product approvals, patents, product width and breath, application dominance, technology lifeline curve. The above data points provided are only related to the company’s focus on the market.
Some of the major market players operating in India gene synthesis market are Thermo Fisher Scientific Inc., Boster Biological Technology, Twist Bioscience, OriGene Technologies, Inc., Eurofins Scientific, GenScript, Merck KGaA, Kaneka Eurogentec S.A, Synbio Technologies, and GCC Biotech (INDIA) Pvt. Ltd.
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