Global Pemphigus Vulgaris Market, By Diagnosis and Treatment (Diagnosis and Treatment), Population Type (Pediatric, Adults, and Geriatric), End User (Hospitals, Specialty Clinics, Research Institutes, and Others), Distribution Channel (Hospitals Pharmacy, Retail Pharmacy, and Online Pharmacy) - Industry Trends and Forecast to 2030.
Pemphigus Vulgaris Market Analysis and Insights
The rising usage and adoption of digital health technologies have enhanced the demand for the market. The major market players focus on various product approvals and availability during this crucial period. In addition, the increase in improved and advanced healthcare facilities also contributes to the rising demand for the market.
The market is expected to grow in the forecast year due to the rise in immune-based skin disorders. The support for the affected patients suffering from pemphigus vulgaris by various NGOs is also expected to drive market growth. Along with this, manufacturers are engaged in R&D activity and approvals in the market. However, the strict regulatory guidelines associated with the treatment procedures and drug approvals is expected to restrain market growth. The increasing demand for personalized medicine is expected to give opportunities to the market. The growing demand for better quality healthcare with all the facilities is expected to boost the market growth. However, the adverse effects associated with the treatment are expected to challenge market growth.
Data Bridge Market Research analyzes that the global pemphigus vulgaris market is expected to reach a value of USD 677.32 million by 2030, at a CAGR of 8.2% during the forecast period. Diagnosis and treatment account for the largest type segment in the market due to the increasing number of pemphigus vulgaris patients among the global population. This market report also covers pricing analysis, patent analysis, and technological advancements in depth.
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Report Metric
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Details
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Forecast Period
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2023 to 2030
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Base Year
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2022
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Historic Years
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2021 (Customizable to 2015 - 2020)
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Quantitative Units
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Revenue in Million, Volumes in Units, and Pricing in USD
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Segments Covered
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Diagnosis and Treatment (Diagnosis and Treatment), Population Type (Pediatric, Adults, and Geriatric), End User (Hospitals, Specialty Clinics, Research Institutes, and Others), Distribution Channel (Hospitals Pharmacy, Retail Pharmacy, and Online Pharmacy)
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Countries Covered
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U.S., Canada, and Mexico, Germany, France, U.K., Italy, Russia, Spain, Netherlands, Switzerland, Belgium, Turkey, and Rest of Europe, China, Japan, India, Australia, South Korea, Singapore, Malaysia, Thailand, Indonesia, Philippines, and Rest of Asia-Pacific, South Africa, Saudi Arabia, U.A.E., Israel, Egypt, and Rest of Middle East and Africa, Brazil, Argentina, and Rest of South America
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Market Players Covered
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Sanofi, Regeneron Pharmaceuticals Inc., Fresenius Kabi AG, Boehringer Ingelheim International GmbH, Johnson & Johnson Services, Inc., RAKSHIT DRUGS PVT. LTD, F. Hoffmann-La Roche Ltd, Pfizer Inc., Celltrion Healthcare Co., Ltd., AbbVie Inc., Novartis AG, Amgen Inc., Merck & Co., Inc., AstraZeneca, Teva Pharmaceutical Industries Ltd, Lilly, Zydus Group, and GSK plc among others.
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Global Pemphigus Vulgaris Market Definition
A rare, chronic autoimmune condition called pemphigus vulgaris is characterized by developing skin and mucous membrane blisters. It is thought to be the most typical variation of the autoimmune blistering illness known as pemphigus. In pemphigus vulgaris, the immune system unintentionally generates antibodies that target desmogleins, a class of proteins necessary for the attachment of skin cells. Blisters develop due to this antibody attack, and skin layers separate. The body can develop blisters anywhere, but the mouth, throat, scalp, face, chest, groyne, and armpits are the most typical locations for them to appear. The rising awareness regarding diseases is expected to drive market growth.
Although the precise origin of pemphigus vulgaris is unknown, it is thought to result from a confluence of genetic predisposition and environmental stimuli. In those who are sensitive, certain things—such as specific drugs, infections, or UV radiation exposure can cause the illness or make it worse. However, strict regulatory guidelines are expected to restrain market growth.
Global Pemphigus Vulgaris Market Dynamics
This section deals with understanding the market drivers, opportunities, restraints, and challenges. All of this is discussed in detail below:
Drivers
- Emerging treatment options for pemphigus vulgaris
Pemphigus vulgaris is a chronic immune system disorder that affects a small percentage of people. As a result, blisters appear on the skin and in the mouth. Although medication can help control it if it is serious. Autoantibodies that target the adhesion molecules between keratinocytes cause the persistent, severe autoimmune bullous illness known as pemphigus. The condition must be managed for an average of two to three years.
Treatment with systemic glucocorticoids can save lives in people with pemphigus vulgaris, but it can also have fatal side effects. Before the necessity to provide systemic glucocorticosteroids, a patient with pemphigus vulgaris and myasthenia gravis was treated for almost five years with the cholinomimetic drugs Mestinon (pyridostigmine bromide), Imuran (azathioprine), and a topical corticosteroid gel.
Thus, emerging treatment options or approaches for pemphigus vulgaris are expected to drive market growth.
- The growing support of NGOs for the affected patients
Numerous Non-Governmental Organizations (NGOs) and patient support groups put in a lot of effort to help those with pemphigus vulgaris by offering assistance, resources, and advocacy. Pemphigus vulgaris-focused local or regional support organizations may exist in particular regions or nations. These organizations can provide community-specific advocacy activities, peer assistance, and local resources.
Thus, growing support by NGOs for patients suffering from pemphigus vulgaris is expected to drive market growth.
Opportunity
- Digital health technologies for treatment management
Digital health technologies have the potential to have a significant influence on the treatment and management of pemphigus vulgaris patients. Dermatologists and other medical professionals can be consulted virtually by patients through telemedicine, eliminating the need for in-person appointments. This can be especially helpful for people with pemphigus vulgaris who may have trouble getting to medical facilities because of mobility problems or restricted access. Regular check-ups, medication monitoring, and follow-up appointments can be facilitated through telemedicine, enabling continuity of care and immediate modifications to treatment programs.
Numerous mobile apps and online tools can be helpful resources for pemphigus vulgaris patients. These platforms can offer self-monitoring tools, medication reminders, and educational resources. Patients can keep track of their symptoms, medications, and disease development, which enables them to actively take part in their own care and interact with medical professionals more efficiently. Numerous clinics and healthcare organizations offer immunological testing and blood tests to patients through their web portals, making it simple for those who encounter difficulties because of various circumstances, including poor accessibility to pathology labs and others.
Thus, digital health solutions or technologies for treatment management are expected to act as an opportunity for market growth.
Challenges/ Restraints
- Adverse effects associated with medications
Medications that inhibit the immune system are used to treat pemphigus vulgaris (PV) to manage the autoimmune reaction. While these drugs can help manage PV, they also have the potential to have harmful side effects. Depending on the medication and the person, the precise side effects may change. Each patient's treatment must be customized based on their unique medical history and comorbid disorders. While receiving the best care possible, patients may suffer minimal disease activity. Medication designed to prevent blister formation is typically used as the first line of treatment. It usually works better at the initial stage.
Thus, adverse effects arising from the medications are expected to act as a challenge to market growth.
- Strict regulatory guidelines
The provision of advice and standards for the diagnosis, treatment, and management of numerous medical disorders, including pemphigus vulgaris, is facilitated by regulatory guidelines. Regulatory agencies and organizations focusing on dermatological or autoimmune illnesses usually establish these guidelines. To ensure the safety, effectiveness, and quality of drugs used to treat pemphigus vulgaris, regulatory agencies may assess and approve them.
To make educated choices about the authorization and supervision of pharmaceuticals, they may consider information from clinical trials, manufacturing procedures, and adverse event reporting systems.
Thus, strict regulatory guidelines are expected to restrain the market growth.
Recent Developments
- In June 2023, AstraZeneca announced that for the treatment of adult patients with refractory generalized myasthenia gravis (gMG) and anti-acetylcholine receptor (AChR) antibody positivity, Soliris (eculizumab) had received approval in China. The only complement inhibitor authorized for the treatment of gMG in China is Soliris. Comprehensive findings from the Phase III REGAIN trial served as the foundation for the clearance by the National Medical Products Administration (NMPA) in China.
- In January 2023, Merck & Co., Inc. announced the FDA has approved KEYTRUDA, Merck's anti-PD-1 therapy, as a single agent for adjuvant therapy following surgical resection and platinum-based chemotherapy for adult patients with stage IB (T2a 4 centimetres [cm]), II, or IIIA non-small cell lung cancer (NSCLC).
Global Pemphigus Vulgaris Market Scope
The global pemphigus vulgaris market is segmented into diagnosis and treatment, population type, end user, and distribution channel. The growth among segments helps you analyze niche pockets of development and strategies to approach the market and determine your core application areas and the difference in your target markets.
Diagnosis and Treatment
- Diagnosis
- Treatment
On the basis of diagnosis and treatment, the market is segmented into diagnosis and treatment.
Population Type
- Pediatric
- Adults
- Geriatric
On the basis of population type, the market is segmented into pediatric, adults, and geriatric.
End User
- Hospitals
- Specialty Clinics
- Research Institutes
- Others
On the basis of end user, the market is segmented into hospitals, specialty clinics, research institutes, and others.
Distribution Channel
- Hospitals Pharmacy
- Retail Pharmacy
- Online Pharmacy
On the basis of distribution channel, the market is segmented into hospitals pharmacy, retail pharmacy, and online pharmacy.
Global Pemphigus Vulgaris Market Regional Analysis/Insights
The market is analyzed, and market size information is provided by diagnosis and treatment, population type, end user, and distribution channel.
The countries covered in this market report are U.S., Canada, and Mexico, Germany, France, U.K., Italy, Russia, Spain, Netherlands, Switzerland, Belgium, Turkey, and Rest of Europe, China, Japan, India, Australia, South Korea, Singapore, Malaysia, Thailand, Indonesia, Philippines, and Rest of Asia-Pacific, South Africa, Saudi Arabia, U.A.E., Israel, Egypt, and Rest of Middle East and Africa, Brazil, Argentina, and Rest of South America.
North America is expected to dominate due to the presence of key market players in the largest consumer market with high GDP. The U.S. is expected to grow due to the rise in technological advancement for pemphigus vulgaris.
The increasing investment in R&D and increasing adoption of personalized medicine for pemphigus vulgaris as an option for the formulation of treatment regimens are expected to boost the market growth. The U.S. dominates the North American region due to the strong presence of advanced technology providers such as Novartis AG, Amgen Inc., Merck & Co., Inc., AstraZeneca, and others. The Germany dominates the Europe region due to the increasing demand from emerging markets and the expansion of healthcare industries. China dominates the Asia-Pacific region due to an increase in healthcare expenditure.
The country section of the report also provides individual market-impacting factors and changes in regulation in the market domestically that impact the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, regulatory acts, and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, and the impact of sales channels are considered while providing forecast analysis of the country data.
Competitive Landscape and Global Pemphigus Vulgaris Market Share Analysis
Global pemphigus vulgaris market competitive landscape provides details by the competitor. Details included are company overview, company financials, revenue generated, market potential, investment in R&D, new market initiatives, production sites and facilities, company strengths and weaknesses, product launch, product trials pipelines, product approvals, patents, product width and breath, application dominance, technology lifeline curve. The above data points provided are only related to the company’s focus on the global pemphigus vulgaris market.
Some of the major players operating in the global pemphigus vulgaris market are Sanofi, Regeneron Pharmaceuticals Inc., Fresenius Kabi AG, Boehringer Ingelheim International GmbH, Johnson & Johnson Services, Inc., RAKSHIT DRUGS PVT. LTD, F. Hoffmann-La Roche Ltd, Pfizer Inc., Celltrion Healthcare Co., Ltd., AbbVie Inc., Novartis AG, Amgen Inc., Merck & Co., Inc., AstraZeneca, Teva Pharmaceutical Industries Ltd, Lilly, Zydus Group, GSK plc., among others.
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