The global lumasiran market is positioned for significant growth, driven by the increasing incidence of primary hyperoxaluria type 1 (PH1) and the rising demand for effective therapeutic solutions. Lumasiran, a small interfering RNA (siRNA) therapeutic agent, has shown efficacy in reducing urinary oxalate levels, thereby addressing a critical unmet need in the treatment of PH1. The FDA’s approval of lumasiran marks a significant milestone in managing this rare metabolic disorder, offering a novel approach to therapy. The market's expansion is further fueled by a growing awareness of rare diseases and an emphasis on improving patient outcomes. As healthcare providers and patients recognize the importance of early intervention and effective treatment options, lumasiran is increasingly seen as a pivotal therapy. Additionally, advancements in research and development, supported by government initiatives and funding, are enhancing the landscape for rare disease treatments. The increasing focus of pharmaceutical companies on innovative therapies and a rising understanding of primary hyperoxaluria are likely to contribute to the market's robust growth, making lumasiran a cornerstone in the management of this rare condition.