Global Iron-Deficiency Anemia Therapy Market, By Therapy (Parenteral Iron Therapy and Oral Iron Therapy), Therapy Area (Obstetrics and Gynecology, Renal Diseases, Congestive Heart Failure (CHF), Oncology, Inflammatory Bowel Disease, and Others), Population (Adults, Geriatric, and Pediatric), End User (Hospitals, Specialty Clinics, Home Care Setting, and Others), Distribution Channel (Hospital Pharmacy, Drug Stores and Retail Pharmacies, and Online Pharmacies) – Industry Trends and Forecast to 2031.
Iron-Deficiency Anemia Therapy Market Analysis and Size
The global iron-deficiency anemia therapy market is experiencing significant growth, driven by the rising incidences of iron deficiency anemia, introduction of novel drugs in the market, and inclination towards social healthcare on women health specifically anemia. The market is characterized by the presence of a large number of players offering a wide range of therapies tailored to meet the diverse needs of healthcare providers in the region.
Data Bridge Market Research analyzes that the global iron-deficiency anemia therapy market is expected to reach USD 10.08 billion by 2031, from USD 4.86 billion in 2023, growing with a CAGR of 10.0% in the forecast period of 2024 to 2031. Rising incidences of iron deficiency anemia is expected to drive the market’s expansion.
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Report Metric
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Details
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Forecast Period
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2024 to 2031
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Base Year
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2023
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Historic Year
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2022 (Customizable 2016-2021)
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Quantitative Units
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Revenue in USD Billion
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Segments Covered
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Therapy (Parenteral Iron Therapy and Oral Iron Therapy), Therapy Area (Obstetrics and Gynecology, Renal Diseases, Congestive Heart Failure (CHF), Oncology, Inflammatory Bowel Disease, and Others), Population (Adults, Geriatric, and Pediatric), End User (Hospitals, Specialty Clinics, Home Care Setting, and Others), Distribution Channel (Hospital Pharmacy, Drug Stores and Retail Pharmacies, and Online Pharmacies)
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Countries Covered
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Mexico, Canada, U.S., U.K., Germany, Italy, France, Spain, Belgium, Switzerland, Turkey, Russia, Netherlands, Rest of Europe, India, China, Japan, Australia, Thailand, Malaysia, South Korea, Philippines, Singapore, Indonesia, Rest of Asia-Pacific, Argentina, Brazil, Rest of South America, South Africa, Egypt, Saudi Arabia, U.A.E., Israel, Rest of Middle East and Africa
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Market Players Covered
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Vifor Pharma Ltd., DAIICHI SANKYO COMPANY, LIMITED, AFT Pharmaceuticals., Sanofi, Pfizer Inc., Fresenius Kabi AG, PHARMACOSMOS Therapeutics Inc, Thorne, Lupin, BLACKMORES, Shield Therapeutics plc, Aspen Pharmacare Australia Pty Ltd. Health Care among others.
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Market Definition
Iron deficiency anemia therapy is a treatment approach aimed at replenishing iron stores and correcting anemia caused by iron deficiency. The primary goal of therapy is to restore normal iron levels and hemoglobin production, thereby improving symptoms such as fatigue, weakness, and shortness of breath. Therapy typically involves oral iron supplementation, which can be in the form of ferrous sulfate, ferrous gluconate, or ferric citrate, and may be administered alone or in combination with other medications to enhance absorption and efficacy. In severe cases, intravenous iron therapy may be necessary, and in some instances, blood transfusions may be required to rapidly increase hemoglobin levels.
Global Iron-Deficiency Anemia Therapy Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:
Drivers
- Rising Incidences of Iron Deficiency Anemia
Anemia is defined as a low concentration of blood hemoglobin. It is a health problem that affects all economical sections of world ranging from low-, middle- and high-income countries. Significant adverse health consequences of anemia along with worse impacts on economic and social development.
Anemia occurs due to various etiologies, with the most common contributor is iron deficiency. Approximately 50% of cases of anemia cases are caused due to iron deficiency, but the ratio probably varies due to various factors.
Other causes of anemia include other deficiencies of micronutrient (e.g. vitamins A, folate, riboflavin and B12), chronic and acute infections (e.g. cancer, tuberculosis, malaria, and HIV), and acquired or inherited disorders that affect synthesis of hemoglobin, red blood cell (RBC) production or survival.
Iron deficiency anemia is said to be the most common form of anemia found globally. In this condition, blood lacks sufficient healthy red blood cells (RBC’s) which functions to carry oxygen to the tissue of the body’s Iron deficiency anemia is caused due to insufficient iron.
The lack of proper nutrition and various inflammations in body, which renders the poor absorption of the iron, leads to increased prevalence of iron deficiency anemia.
For instance,
- According to a report by India Spend, published in 2016, 20% of maternal deaths in India were caused by anemia and was the associate cause in 50% of maternal deaths in October 2016. Low birth weight among babies and risking them for lifelong issues involving physical growth and cognitive development is caused by anemia. According to statistics, the efficiency of anemic children reduces to 2.5% as adults compared to their healthier peers.
- According to Global Nutrition Report 2017, it reported that just over half (51%) of women of reproductive age (15 to 49 years) are anemic in India and according to the report in the fourth National Family Health Survey (NFHS-IV) in 2015-16 it is estimated that 53% of the women were anemic in India in the reproductive age
Introduction of Novel Drugs in the Market
Innovation drives progress, the availability of novel drugs, lead products and biological products often means new hope and better treatment options for patients and advancement in health care for public worldwide. Some of the products are new and innovative with novel approach that have never been used in clinical practice and have potential benefits to cure the persisting ailment in the population worldwide. The various drugs and therapies are made with advanced research and development and thorough testing using subjects to check their efficiency.
For instance,
- In December 2023, according to an article published by FDA, the U.S. FDA approved two landmark treatments, Casgevy and Lyfgenia, as the first cell-based gene therapies for sickle cell disease (SCD) in patients 12 years and older. Notably, Casgevy is the first FDA-approved treatment to use novel genome editing technology, marking a significant advancement in gene therapy
- These breakthroughs will drive the global iron-deficiency anemia therapy market by highlighting the potential for innovative treatments and encouraging further research and development in anemia-related therapies
- In September 2023, according to an article published by GSK plc., GSK plc. announced FDA approval of Ojjaara (momelotinib) for treating intermediate or high-risk myelofibrosis, including primary and secondary myelofibrosis, in adults with anemia. Ojjaara, a once-daily oral JAK1/JAK2 and ACVR1 inhibitor, is the only approved treatment for both newly diagnosed and previously treated myelofibrosis patients with anemia, addressing anemia, constitutional symptoms, and splenomegaly.
Opportunity
- Increasing Research and Development Activities
Herbs, fungi and plants for curing anemia have been used in medicinal traditions indigenous for millennia. The increased prevalence of anemia worldwide is causing a social problem in the world leading to more rigorous research and development need in the respected field. After decades of persistent advocacy and education, rigorous research and development employing iron deficiency anemia as tools of healing and discovery are abundant.
Currently, various research studies are taking place in private practice sites and in research institutions supported by for-profit and non-profit organizations, along with individual research studies. This research includes clinical trials for intravenous therapy for the treatment of iron deficiency anemia associated with chronic heart disease, chronic kidney diseases dependent on dialysis or non-dependent of dialysis.
For instance,
- In March 2022, according to an article published by National Heart, Lung, and Blood Institute, NHLBI researchers have contributed to treatments for aplastic anemia, a rare condition where the bone marrow fails to produce enough blood cells. They developed immunosuppressant drugs to manage this disorder. NHLBI-funded research continues to explore the causes of anemia, investigating red blood cell production in healthy individuals and those with anemia. Additionally, the NHLBI and NCI launched the Blood and Marrow Transplant Clinical Trials Network in 2001 to advance transplantation therapies, potentially curing certain types of anemia
- These efforts present opportunities for the global iron-deficiency anemia therapy market by fostering innovation in treatment approaches, including genetic therapies, and supporting clinical trials that could lead to new, effective treatments for anemia worldwide
Restraint/Challenge
- Limitation in Diagnosing Iron Deficiency Anemia in Inflammatory Conditions
Iron deficiency anemia is a major health problem across globe, which represents one of the growing nonlethal disease situations across globe and is frequently seen in ordinary clinical practice. Timely prognosis and diagnosis are crucial because of the important role played by iron in the functioning of all organ systems. In spite of its prevalence, iron deficiency is generally overlooked, in patients with inflammatory conditions, mostly due to the mixture of symptoms and definitions provided in clinical preparation guidelines.
Usually, the most well-known risk groups for iron deficiency are the malnourished people, those who needs high iron inputs, such as adolescents or pregnant women, and individuals with chronic blood loss, for instance, from gastrointestinal bleeding or heavy uterine. The growing attention is now being shifted towards the iron status of patients associated with inflammatory conditions, which incline them to iron deficiency.
The most frequent of these are Chronic Kidney Disease (CKD), Chronic Heart Failure (CHF), and Inflammatory Bowel Disease (IBD). Estimation of iron deficiency in patients associated with inflammatory diseases is least diagnosed due to lack of diagnosing measures or markers.
For instance,
- In July 2022, according to an article published by PubMed Central, diagnosing and treating iron-deficiency anemia (IDA) relies on accurate detection of iron deficiency, which is complicated by factors like inflammation, diet, and metabolic variations. Current biomarkers such as hemoglobin (Hb), serum ferritin, and transferrin saturation levels are affected by these factors, making them unreliable in certain conditions. For instance, ferritin levels can rise during inflammation, masking true iron levels. The use of multiple markers like the sTfR-F index shows promise in overcoming these challenges, but there remains a need for more robust diagnostic tools
- This diagnostic complexity poses a significant challenge for the global iron-deficiency anemia therapy market, necessitating the development of more accurate and sensitive diagnostic methods that can reliably identify and monitor iron status in diverse patient populations, including those with underlying inflammatory conditions or specific genetic disorders like sickle cell anemia
- In 2018, according to a report published in the international journal of chronic diseases by Department of Medicine, Agaplesion Markus Hospital, Goethe University, Germany and Interdisciplinary Crohn Colitis Center Rhein-Main, Germany. The estimates of iron deficiency in groups of people having inflammatory conditions have changed a lot between studies due to contradictory definitions and diverse patient assortment criteria. They found that approximately 24–85% of patients with CKD, 50% of patients with CHF and 45% of patients with IBD are iron-deficient
Recent Developments
- In June 2023, GSK has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP), recommending the authorization of daprodustat for the treatment of symptomatic anemia associated with chronic kidney disease (CKD) in adults undergoing chronic maintenance dialysis. This recommendation marks a significant step towards providing a new therapeutic option for managing anemia in CKD patients on long-term dialysis, addressing an important unmet medical need in this population
- In March 2024, Vafseo approved by the U.S. FDA for the treatment of anemia due to chronic kidney disease in dialysis-dependent adult patients. CSL Vifor is pleased that its partner Akebia Therapeutics, Inc. announced that the U.S. Food and Drug Administration (FDA) has approved Vafseo (vadadustat) tablets for the treatment of anemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least three months. Vafseo is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) developed by Akebia
- In February 2024, Lupin launched a Cyanocobalamin Nasal Spray, 500 mcg/spray (One Spray per Device), after having received an approval from the United States Food and Drug Administration (U.S. FDA)
- In December 2023, Novartis receives FDA approval for Fabhalta (iptacopan), offering superior hemoglobin improvement in the absence of transfusions as the first oral monotherapy for adults with PNH announced that the U.S. Food and Drug Administration (FDA) approved Fabhalta (iptacopan) as the first oral monotherapy for the treatment of adults with Paroxysmal Nocturnal Hemoglobinuria (PNH). Fabhalta is a Factor B inhibitor that acts proximally in the alternative complement pathway of the immune system, providing comprehensive control of red blood cell (RBC) destruction within and outside the blood vessels (intra- and extravascular hemolysis [IVH and EVH])
- In March 2024, Ferinject approved by Health Canada for the treatment of iron deficiency anemia in adult and pediatric patients and iron deficiency in adult patients with heart failure announced that Health Canada has authorized Ferinject (ferric carboxymaltose) for the intravenous (IV) treatment of iron deficiency anemia in adult and pediatric patients one year of age and older when oral iron preparations are not tolerated or are ineffective, as well as for the treatment of iron deficiency in adult patients with heart failure
Global Iron-Deficiency Anemia Therapy Market Scope
The global iron-deficiency anemia therapy market is segmented into five notable segments based on therapy, therapy area, population, end user, and distribution channel. The growth amongst these segments will help you analyze major growth segments in the industries and provide the users with a valuable market overview and market insights to make strategic decisions to identify core market applications.
Therapy
- Parenteral Iron Therapy
- Oral Iron Therapy
On the basis of therapy, the market is segmented into parenteral iron therapy and oral iron therapy.
Therapy Area
- Obstetrics and Gynecology
- Renal Diseases
- Congestive Heart Failure (CHF)
- Oncology
- Inflammatory Bowel Disease
- Others
On the basis of therapy area, the market is segmented into obstetrics and gynecology, renal diseases, Congestive Heart Failure (CHF), oncology, inflammatory bowel disease and others.
Population
- Adults
- Geriatric
- Pediatric
On the basis of population, the market is segmented into adults, geriatric, and pediatric.
End User
- Hospitals
- Specialty Clinics
- Home Care Setting
- Others
On the basis of end user, the market is segmented into hospitals, specialty clinics, home care setting, and others.
Distribution Channel
- Hospital Pharmacy
- Drug Stores and Retail Pharmacies
- Online Pharmacies
On the basis of distribution channel, the market is segmented into hospital pharmacy, drug stores, retail pharmacies, online pharmacies.
Global Iron-Deficiency Anemia Therapy Market Regional Analysis/Insights
The global iron-deficiency anemia therapy market is analyzed and market size insights and trends are provided based on therapy, therapy area, population, end user, and distribution channel as referenced above.
The countries covered in this market report are Mexico, Canada, U.S., U.K., Germany, Italy, France, Spain, Belgium, Switzerland, Turkey, Russia, Netherlands, rest of Europe, India, China, Japan, Australia, Thailand, Malaysia, South Korea, Philippines, Singapore, Indonesia, rest of Asia-Pacific, Argentina, Brazil, rest of South America, South Africa, Egypt, Saudi Arabia, U.A.E., Israel, rest of Middle East and Africa.
North America is expected to dominate the global iron-deficiency anemia therapy market due to its advanced healthcare infrastructure, The U.S. is expected to dominate the North America region due to high prevalence of the condition, robust reimbursement policies, and significant investments in research and development. The U.K. is expected to dominate the Europe region due to government inclination towards social healthcare on women health specifically anemia. India is expected to dominate the Asia-Pacific iron-deficiency anemia therapy market.
The country section of the report also provides individual market-impacting factors and changes in market regulation that impact the current and future trends of the market. Data points such as downstream and upstream value chain analysis, technical trends, Porter's five forces analysis, and case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs, and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and Global Iron-Deficiency Anemia Therapy Market Share Analysis
The global iron-deficiency anemia therapy market competitive landscape provides details of competitors. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points provided are only related to the companies' focus on the global iron-deficiency anemia therapy market.
Some of the major players operating in the global iron-deficiency anemia therapy market are Vifor Pharma Ltd., Daiichi Sankyo Company, Limited, AFT Pharmaceuticals., Sanofi, Pfizer Inc., Fresenius Kabi AG, Pharmacosmos Therapeutics Inc, Thorne, Lupin, Blackmores, Shield Therapeutics plc, Aspen Pharmacare Australia Pty Ltd. Health Care among others.
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