Global Hyaluronic Acid Market, By Form (Native/Linear Hyaluronic Acid and Cross-Linked Hyaluronic Acid), Grade (Cosmetic Grade, Pharmaceutical Grade, and Food Grade), Type (Sodium Hyaluronate, Hydrolyzed Hyaluronic, Sodium Acetylated Hyaluronic Acid), Route of Administration (Parenteral, Topical, and Oral), Source (Microbial Fermentation, Animal Based, and Plant Based), Dosage Form (Powder, Solution, and Gel), Application (Aesthetics & Cosmetics, Osteoarthritis, Pharmaceutical API, Dietary Supplements, Ophthalmology, and Others) End User (Dermatology Clinics, Cosmetic Surgery Centers, Medical Spas and Beauty Centers, Others), Distribution Channel (Retail Sales and Direct Tender) - Industry Trends and Forecast to 2031.
Hyaluronic Acid Market Analysis and Insights
The driving factors which is responsible for the growth of the global hyaluronic acid market are the rising application of hyaluronic acid in medical and pharmaceutical industry. These platforms are the expanding application spectrum has fueled significant market growth, reflected in rising revenues across the HA industry. However, a significant restraint for the market is side effects related to hyaluronic acid.
Data Bridge Market Research analyses that the global hyaluronic acid market is expected to reach USD 17.64 billion by 2031 from USD 9.35 billion in 2023, growing at a CAGR of 8.3% in the forecast period of 2024 to 2031.
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Report Metric
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Details
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Forecast Period
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2024 to 2031
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Base Year
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2023
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Historic Years
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2022 (Customizable to 2016-2021)
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Quantitative Units
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Revenue in USD Billion
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Segments Covered
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Form (Native/Linear Hyaluronic Acid and Cross-Linked Hyaluronic Acid), Grade (Cosmetic Grade, Pharmaceutical Grade, and Food Grade), Type (Sodium Hyaluronate, Hydrolyzed Hyaluronic, Sodium Acetylated Hyaluronic Acid), Route of Administration (Parenteral, Topical, and Oral), Source (Microbial Fermentation, Animal Based, and Plant Based), Dosage Form (Powder, Solution, and Gel), Application (Aesthetics & Cosmetics, Osteoarthritis, Pharmaceutical API, Dietary Supplements, Ophthalmology, and Others) End User (Dermatology Clinics, Cosmetic Surgery Centers, Medical Spas and Beauty Centers, Others), Distribution Channel (Retail Sales and Direct Tender)
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Country covered
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U.S., Canada, Mexico, Germany, U.K., Italy, France, Spain, Russia, Switzerland, Turkey, Belgium, Netherlands, Rest of Europe, Japan, China, South Korea, India, Singapore, Thailand, Indonesia, Malaysia, Philippines, Australia, Rest of Asia-Pacific, Brazil, Argentina, Rest of South America, South Africa, Egypt, Saudi Arabia, U.A.E., Israel, and Rest of Middle East and Africa
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Market Players Covered
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Fufeng group, Fidia Farmaceutic S.p.A, DSM, Asahi Kasei Corporation, Nestle, AbbIVe Inc., Galderma, Virchow biotech, Givaudan, Anika Therapeutics, Inc, Seikagaku corporation, Merz North America Inc., Contipro a.s., and Bloomage Biotech Co., Ltd, among others.
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Market Definition
Hyaluronic Acid (HA) also called hyaluronan, is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is a glycosaminoglycan with exceptional hydrating properties, capable of holding large amounts of water. In skincare and medical applications, HA is highly valued for its ability to moisturize, plump, and rejuvenate the skin, as well as for its role in promoting joint health and wound healing.
Global Hyaluronic Acid Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below
Drivers
Growing Consumption Trends of Hyaluronic Acid Globally
- The increasing trend of Hyaluronic Acid (HA) reflects its growing popularity and utilization across various industries. In skincare, HA is prized for its ability to hydrate and plump the skin, reducing the appearance of fine lines and wrinkles, hence its prevalence in moisturizers, serums, and other beauty products. Moreover, the medical field sees HA used in treatments like dermal fillers for cosmetic enhancements and in osteoarthritis therapy to lubricate joints and reduce pain. Its biocompatibility and natural occurrence in the body contribute to its widespread acceptance and use. As research continues to uncover its versatile applications, the demand for HA in both cosmetic and medical sectors is expected to further escalate
Rising initiatives by Market Players
- Healthcare market players are exhibiting a growing initiative in addressing the challenges of Hyaluronic Acid (HA) utilization, spurred by increasing demand and awareness of its therapeutic potential. Pharmaceutical companies are intensifying research and development efforts to innovate novel formulations and delivery systems for HA-based treatments, aiming to enhance efficacy and patient outcomes. Additionally, medical device manufacturers are investing in advanced technologies to improve the production and application of HA-based products, expanding their reach across various medical specialties such as orthopedics, ophthalmology, and dermatology. Furthermore, collaborations between industry stakeholders and academic institutions are fostering a deeper understanding of HA's mechanisms of action and its diverse clinical applications, driving forward the development of new treatment modalities. This collective initiative reflects a concerted effort within the healthcare sector to harness the full therapeutic benefits of HA and meet the evolving needs of patients worldwide.
Opportunity
- Increasing Technological Advancements in Hyaluronic products
The increasing technological advancement in Hyaluronic Acid (HA) has revolutionized various fields, particularly in medicine and cosmetics. HA, a naturally occurring substance in the body, is renowned for its ability to retain moisture and promote tissue hydration and elasticity. Recent innovations have led to the development of advanced HA-based products with enhanced properties and applications. In medicine, HA is widely used in orthopedics for joint lubrication and cushioning, in ophthalmology for eye surgery, and in dermatology for soft tissue augmentation and wound healing. Moreover, in the cosmetic industry, HA-based dermal fillers and skincare products are gaining popularity for their anti-aging and moisturizing effects. Technological breakthroughs, such as novel manufacturing techniques and molecular modifications, are continuously improving the efficacy, longevity, and safety profile of HA products, paving the way for further advancements and diversified applications in healthcare and beyond.
Restraints
Challenges
- Side Effects Associated with Hyaluronic Acid
Hyaluronic Acid (HA) is a naturally occurring substance found in the body, often used in medical and cosmetic treatments. While generally well-tolerated, side effects can occur, particularly with HA injections for cosmetic purposes. Common side effects include temporary redness, swelling, bruising, and tenderness at the injection site. In rare cases, allergic reactions may occur, manifesting as itching, rash, or difficulty breathing. Additionally, improper injection technique or placement can result in lumps or unevenness in the skin. It's essential to discuss potential risks and benefits with a healthcare professional before undergoing any HA treatment, ensuring a personalized approach and minimizing the risk of adverse effects.
- Safety Concerns with Hyaluronic Acid Products
Safety concerns related to hyaluronic acid are a significant challenge, particularly given its widespread use in cosmetic and medical applications. While hyaluronic acid is generally considered safe and is naturally present in the human body, potential risks arise from its synthetic or extracted forms used in dermal fillers and other treatments. Adverse reactions can include allergic responses, infections, and granuloma formation, particularly if the substance is not properly purified or administered. Additionally, improper injection techniques can lead to complications such as vascular occlusion, which can cause tissue necrosis and, in severe cases, blindness. Ensuring the safety of hyaluronic acid products thus requires stringent quality control, thorough clinical testing, and professional administration by qualified healthcare providers.
Recent Developments
- In March 2021, DSM extends its hyaluronic acid range with the launch of HYA-ACT™ line. Royal DSM, a global science-based company announces the launch of three different forms of hyaluronic acid. With the new HYA-ACT™ range, DSM strengthens its hyaluronic acid portfolio to deliver on growing market expectations for less-invasive, reliable and effective beauty care solutions
- In August 2020, Asahi Kasei has established industrial manufacturing technology for Hyaluronic Acid (HA) nanogel as a new pharmaceutical excipient, and is providing samples to prospective customers in order to commercialize the product. The commercialization of HA nanogel would expand the product lineup by adding a Drug Delivery System (DDS) base material for injection formulations.This HA nanogel is expected to improve the Quality of Life (QOL) for patients by enabling the low-toxicity solubilization of insoluble drugs, facilitating the formulation of biopharmaceuticals such as proteins and peptides
- In June 2020, Nestlé Health Science partners with Bioiberica to deliver innovative nutrition in joint health and mobility. Nestlé Health Science is incorporating Bioiberica’s patented ingredient, Mobilee, into its MERITENE Mobilis joint-health drink mix. Mobilee is a natural extract containing a high concentration of hyaluronic acid and other components, including collagen and polysaccharides, which have scientifically shown to contribute to the maintenance of joint and muscle health
- In March 2024, the FDA has approved Juvéderm Voluma XC (AbbVie) for injection in the temple region to treat moderate to severe temple hollowing in adults aged 21 and older. It is the hyaluronic acid dermal filler to receive FDA approval for this specific use, with results lasting up to 13 months
- In December 2021, Allergan announced that the company had completed its acquisition of Soliton, Inc. This has helped the company in expanding its aesthetic product portfolio in the market
Global Hyaluronic Acid Market Scope
The global hyaluronic acid market is segmented into nine notable segments based on form, grade, type, route of administration, source, dosage form, application, end user, and distribution channel.
The growth among segments helps you analyze niche pockets of growth and strategies to approach the market and determine your core application areas and the differences in your target markets.
Form
- Native/Linear Hyaluronic Acid
- Cross-Linked Hyaluronic Acid
On the basis of form, the market is segmented into native/linear hyaluronic acid, cross-linked hyaluronic acid.
Grade
- Cosmetic Grade
- Pharmaceutical Grade
- Food Grade
On the basis of grade, the market is segmented into cosmetic grade, pharmaceutical grade, and food grade.
Type
- Sodium Hyaluronate
- Hydrolyzed Hyaluronic
- Sodium Acetylated Hyaluronic Acid
On the basis of type, the market is segmented into sodium hyaluronate, hydrolyzed hyaluronic, and sodium acetylated hyaluronic acid.
Route of Administration
- Parenteral
- Topical
- Oral
On the basis of route of administration, the market is segmented into parentral, topical, and oral.
Source
- Microbial Fermentation
- Animal Based
- Plant Based
On the basis of source, the market is segmented into microbial fermentation, animal based, and plant based.
Dosage Form
- Powder
- Solution
- Gel
On the basis of dosage form, the market is segmented into powder, solution, and gel.
Application
- Aesthetics & Cosmetics
- Osteoarthritis
- Pharmaceutical API
- Dietary Supplements
- Ophthalmology
- Others
On the basis of application, the market is segmented into aesthetics & cosmetics, osteoarthritis, pharmaceutical API, dietary supplements, ophthalmology, and others.
End User
- Dermatology Clinics
- Medical Spas and Beauty Centers
- Cosmetic Surgery Centers
- Pharmaceutical Industry
- Food Industry
- Others
On the basis of end user, the market is segmented into dermatology clinics, cosmetic surgery centers, medical spas and beauty centers, pharmaceutical industry, food industry, and others.
Distribution Channel
- Retail Sales
- Direct Tender
On the basis of distribution channel, the market is segmented into retail sales and direct tender.
Global Hyaluronic Acid Market Regional Analysis/Insights
The global hyaluronic acid market is analyzed and market size insights and trends are provided by form, grade, type, route of administration, source, dosage form, application, end user, and distribution channel.
The countries covered in the global hyaluronic acid market are U.S., Canada, Mexico, Germany, U.K., Italy, France, Spain, Russia, Switzerland, Turkey, Belgium, Netherlands, rest of Europe, Japan, China, South Korea, India, Singapore, Thailand, Indonesia, Malaysia, Philippines, Australia, rest of Asia-Pacific, Brazil, Argentina, rest of South America, South Africa, Egypt, Saudi Arabia, U.A.E., Israel, and rest of Middle East and Africa.
North America is expected to dominate the global hyaluronic acid market due to strategic initiatives taken by market players in the region. U.S. is expected to dominate the North America hyaluronic acid market due to increasing research and development in the country. Germany is expected to dominate the Europe hyaluronic acid market due to presence of multifaceted consumption methods of hyaluronic acid in the region. Japan is expected to dominate the Asia-Pacific hyaluronic acid market due to technological advancements in hyaluronic acid products in the region.
The country section of the report also provides individual market impacting factors and changes in market regulation that impact the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and Global Hyaluronic Acid Market Share Analysis
The global hyaluronic acid market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in R&D, new market initiatives, company strengths and weaknesses, product launch, product approvals, application dominance, and product type lifeline curve. The above data points provided are only related to the company’s focus on the market.
Some of the major players operating in this market are Fufeng group, Fidia Farmaceutic S.p.A, DSM, Asahi Kasei Corporation, Nestle, AbbIVe Inc., Galderma, Virchow biotech, Givaudan, Anika Therapeutics, Inc, Seikagaku corporation, Merz North America Inc., Contipro a.s., and Bloomage Biotech Co., Ltd, among others.
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