Human African trypanosomiasis also known as sleeping sickness, is a parasitic disease caused by Trypanosoma species transmitted through tsetse flies. It is endemic to sub-Saharan Africa, where it poses a significant public health threat, especially in rural areas. The market for HAT diagnostics and treatments has been evolving with the development of more effective drugs and diagnostic methods. Recent advancements include improved treatments such as eflornithine and nifurtimox, used in combination for better efficacy. Diagnostic techniques have also improved, with blood smears and lumbar punctures being standard methods. However, challenges remain, including the high cost of drugs, limited access to healthcare in endemic areas, and the need for widespread screening. The market is driven by the increasing awareness of the disease, funding from global health organizations, and efforts to eliminate the disease in affected regions. The introduction of more affordable and accessible treatments and diagnostics continues to drive market growth.