Global Cryo-Electron Microscopy Market, By Product Type (Hardware, Software), Method Type (Electron Crystallography, Single Particle Analysis, Cryo-Electron Tomography, Others), Nano Formulations (Lipid Nanoparticle Formulations (LNFS), Metal Oxide Formulations, Metal Formulations, Others), Technology (Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Nuclear Magnetic Resonance (NMR) Microscopy), Mounting Technique (Surface Mounting, Edge Mounting, Film Emulsion Mounting, Rivet Mounting, Others), Application (Biological Science, Material Science, Nanotechnology, Lifesciences, Medical, Semiconductors, Others) End User (Research Laboratories and Institutes, Forensic and Diagnostic Laboratories, Pharmaceutical and Biotechnology Companies, Contract Research Organization, Others), Distribution Channel (Direct Tenders, Third Party Distribution, Others) Industry Trends and Forecast to 2030.
Cryo-Electron Microscopy Market Analysis and Insights
The global cryo-electron microscopy market is expected to grow in the forecast year due to the rise in market players and the availability of advanced services. Along with this, manufacturers are engaged in R&D activity for launching novel services in the market. The increasing research in the development of nanotechnology is further boosting market growth. However, the high cost of the electron microscopy setup might hamper the growth of the global cryo-electron microscopy market in the forecast period.
The global cryo-electron microscopy market is expected to grow in the forecast period of 2023 to 2030. Data Bridge Market Research analyses that the market is growing with a CAGR of 8.7% in the forecast period of 2023 to 2030 and is expected to reach USD 1,533.08 million by 2030.
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Report Metric
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Details
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Forecast Period
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2023 to 2030
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Base Year
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2022
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Historic Years
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2021 (Customizable to 2020-2016)
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Quantitative Units
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Revenue in USD Million
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Segments Covered
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By Product Type (Hardware, Software), Method Type (Electron Crystallography, Single Particle Analysis, Cryo-Electron Tomography, Others), Nano Formulations (Lipid Nanoparticle Formulations (LNFS), Metal Oxide Formulations, Metal Formulations, Others), Technology (Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Nuclear Magnetic Resonance (NMR) Microscopy), Mounting Technique (Surface Mounting, Edge Mounting, Film Emulsion Mounting, Rivet Mounting, Others), Application (Biological Science, Material Science, Nanotechnology, Lifesciences, Medical, Semiconductors, Others) End User (Research Laboratories and Institutes, Forensic and Diagnostic Laboratories, Pharmaceutical and Biotechnology Companies, Contract Research Organization, Others), Distribution Channel (Direct Tenders, Third Party Distribution, Others).
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Countries Covered
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U.S., Canada, France, U.K., Germany, Finland, Netherlands, Denmark, Sweden, Switzerland, Belgium, Spain, Rest of Europe, China, Japan, Australia, Singapore, India, South Korea, Taiwan, Rest of Asia-Pacific, Brazil, Saudi Arabia, Israel, South Africa, Rest of Middle East and Africa.
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Market Players Covered
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Thermo Fisher Scientific Inc., Olympus Corporation, OPTIKA, Helmut Hund Gmbh, Labindia Instruments, JEOL Ltd., Leica Microsystems, KEYENCE CORPORATION., ZEISS International, Molecular Devices, LLC., Nikon Instruments Inc., Intertek Group plc, Caliber Imaging & Diagnostics, Lasertec Corporation, Thorlabs, Inc., Oxford Instruments, Hamamatsu Photonics K.K., NanoFocus AG, HORIBA, Ltd., Labomed, Inc., Creative Biostructure, Gatan, Inc., and Hitachi High-Tech Corporation among others.
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Market Definition
Cryo-electron microscopy is a technique that uses electron microscopy to image frozen-hydrated samples at cryogenic temperatures. Specimens can be studied in their natural state without using colors or fixatives, allowing for the study of appropriate viruses, cellular structures, and protein diversity at molecular resolution.
A computer is then used to process and calculate a large number of 2D (two‐dimensional) images, and reconstruct the 3D (three‐dimensional) structure of the biomacromolecule. 3D reconstruction is used to deduce 3D structure from 2D images. Thus cryo‐EM has made great achievements in the determination of macromolecular structure, especially the structures of supramolecular systems. The breakthrough of this technology has led to a revolution in structural biology.
Global Cryo-Electron Microscopy Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:
Drivers
- RISING TECHNOLOGICAL ADVANCEMENTS IN MICROSCOPY
Digitization, live-cell imaging, super-resolution, and high throughput techniques are examples of technological developments in microscopy. These developments aid in cutting back on product and testing expenses. Expansion microscopes, Scanning Helium Microscopes (SHeM), multi-view microscopes, and integrated microscopy processes are recent advancements in microscope technology.
The most recent development in the market for sample preparation and electron microscopy is digital microscopy. Digital imaging provides superior image resolution and precision, which results in fewer distorted images and better sample viewing. The development of entire slide scanning devices has expedited the use of digital microscopy. These systems provide detailed specimen visualization using 2D and 3D images for application in research and development, forensics, quality assurance, and failure analysis.
Therefore, various technological advancements in the field of microscopy include developments in AI, automation, and continuous improvements in super-resolution microscopy. The manufacturers are continuously adding inputs to improve AI and automation of their microscopes, allowing for faster imaging and less sample prep. New capabilities are expected to drive the global cryo-electron microscopy market growth.
- RAPID DEVELOPMENTS OF NANOTECHNOLOGY
Many disciplines, including health, the space program, the manufacture of fabrics, food, fuel cells, solar cells, and water purification, have benefited from nanotechnology. Nanotechnology is the subject of several research and development projects, which is seen to be one of the factors promoting the expansion of this market.
Cryo-electron microscopy is a well-known and advanced tool used to visualize high-resolution images of biological samples. It provides the functional and morphological information of the tissues and cells and is used in nanotechnology to evaluate nanoparticle penetration in the desired location.
The rise in the prevalence of nanotechnology in the life science domain and the development and recent advancement in nanoparticles impact and healthily increase microscopy usage and may drive the market in the forecasted period.
RESTRAINTS
- HIGH COST OF ELECTRON MICROSCOPY SETUP
With the recent advancement, the increase in research and development among the players and the prevalence of nanotechnology in the domain lead to more prices of microscopy units for high-resolution imaging of the samples. For various causes, such as various research and developments in biological models, and life sciences studies, the imaging model grew, and with the increase in advancement, the prices are also high.
Despite the high cost of the setup, even the parts of the microscope and maintenance of the microscopy unit are very costly, and medium-level or low-level labs cannot afford the microscopy.
Hence, an increase in the research and development in the life science domain is leading to more advancement in microscopy, and that advancement is continuously increasing the price of the microscopy and its units, which may hamper the growth of the global cryo-electron microscopy market.
- DISADVANTAGES OF USING CRYO-ELECTRON MICROSCOPY
Cryo-electron microscopy is used in a variety of fields. Nanoparticle research relies heavily on electron microscopy for the visualization of small particles. Pharmaceutical companies doing drug research utilize electron microscopy to help predict the behavior structure of drugs and biological matter. In the case of pharmaceutical research, a 3D visualization is extremely useful, and cryo-electron microscopy is majorly used for the proposes of least damage to the sample to obtain a usable image. Therefore, the disadvantages of using cryo-electron microscopy are expected to hinder market growth in the upcoming years.
OPPORTUNITIES
- RISING HEALTHCARE EXPENDITURE
Healthcare expenditure has increased worldwide as people's disposable income in various countries has increased. Moreover, to accomplish the population requirements, government bodies and healthcare organizations are taking the initiative to accelerate healthcare expenditure. The rise in healthcare expenditure simultaneously helps healthcare settings to improve their treatment facilities for various diseases, which has been highly prevalent in recent years.
Growing healthcare expenditure is also beneficial for further economic and healthcare sector growth. It is primarily fruitful as it significantly affects the development of better and more advanced therapeutic options with various drugs and other treatment products. Thereby surge in healthcare expenditure is a greater opportunity for the market.
Increasing rates of various types of disease and their severity are widely seen among people globally. The dramatic rise in research quality and increasing research opportunities is because of various strategic initiatives the market players take. They are taking initiatives such as product launch, collaborations, mergers, acquisitions, and many more over the years and is expected to lead and create more opportunities in the market.
- STRATEGIC INITIATIVES BY MARKET PLAYERS
Increasing rates of various types of disease and their severity are widely seen among people globally. The dramatic rise in research quality and increasing research opportunities is because of various strategic initiatives the market players take. They are taking initiatives such as product launch, collaborations, mergers, acquisitions, and many more over the years and is expected to lead and create more opportunities in the market.
These strategic product launches, acquisitions, and mergers done by major companies in the electron microscopy market have opened up opportunities for companies in various regions. This strategy allows the companies to strengthen their footprints in the market. Therefore, it is projected that strategic initiative is the golden opportunity for the market players to accelerate their revenue growth in the market.
CHALLENGES
- LACK OF SKILLED PROFESSIONALS
Physicists and laboratory technicians can easily operate basic compound microscopes; however, skilled personnel is required to develop advanced microscopes. The lack of qualified personnel who are unable to use these instruments could curb the growth of the global cryo-electron microscopy market over a forecast period.
Moreover, rapid technological advancement in this field also led to the lack of skilled professionals. The lack of skilled professionals poses a major challenge while handling device devices in some regions worldwide.
- AVAILABILITY OF OPEN-SOURCE MICROSCOPY SOFTWARE
The availability of open-source software is a challenge for this market. Any programmer with access to the software can inspect and improve that program or, if required, fix any issues. In contrast, most software solutions available in the market are closed-source, proprietary, and expensive, whereas open-source software is usually free.
Some free, open-source confocal microscopy analysis solutions are ImageJ/FIJI, cell profiler/cell analyst, Volume Integration and Alignment System (VIAS), and L-measure. Most small-scale end users, academic institutes, and research centers show a high preference for open-source solutions, which directly hampers the demand for licensed closed-source software.
Thus, this signifies that the availability of open-source microscopy software may challenge market growth.
Recent Developments
- In May 2022, Thermo Fisher Scientific Inc., the world leader in serving science, introduced the Thermo Scientific Glacios 2 Cryo-Transmission Electron Microscope (Cryo-TEM), a powerful microscope with new automation and high-resolution imaging capabilities designed to help cryo-Electron Microscopy (cryo-EM) researchers of varying experience levels accelerate structure-based drug discovery. This advanced, fast, and cost-efficient method for drug design may enable customers to accelerate the pace of research for debilitating disorders such as Alzheimer's, Parkinson's, and Huntington's diseases, as well as research for cancer and gene mutations. This has helped the company to increase its global presence in the market.
- In June 2022, Hitachi High-Tech Corporation announced the launch of the AFM100 Pro High-Sensitivity Scanning Probe Microscope System, a high-end scanning probe microscope (AFM*1/SPM*2) equipped with a newly developed high-sensitivity optical head that improves sensitivity when measuring physical properties and enables measurement at atomic and molecular scales. This has helped the company to increase its global presence.
Global Cryo-Electron Microscopy Market Scope
The global cryo-electron microscopy market is segmented into product type, method type, nano formulations, technology, mounting technique, application, end user, and distribution channel. The growth amongst these segments will help you analyze meager growth segments in the industries and provide the users with a valuable market overview and market insights to make strategic decisions to identify core market applications.
Product Type
- Hardware
- Software
On the basis of product type, the global cryo-electron microscopy market is segmented into hardware, software.
Method Type
- Electron Crystallography
- Single Particle Analysis
- Cryo-Electron Tomography
- Others
On the basis of method type, the global cryo-electron microscopy market is segmented into electron crystallography, single particle analysis, cryo-electron tomography, others.
Nano Formulations
- Lipid Nanoparticle Formulations (LNFS)
- Metal Oxide Formulations
- Metal Formulations
- Others
On the basis of nano formulations, the global cryo-electron microscopy market is segmented into lipid nanoparticle formulations (LNFS), metal oxide formulations, metal formulations, others.
Technology
- Transmission Electron Microscopy (TEM)
- Scanning Electron Microscopy (SEM)
- Nuclear Magnetic Resonance (NMR) Microscopy
On the basis of technology, the global cryo-electron microscopy market is segmented into transmission electron microscopy (TEM), scanning electron microscopy (SEM), and nuclear magnetic resonance (NMR) microscopy.
Mounting Technique
- Surface Mounting
- Edge Mounting
- Film Emulsion Mounting
- Rivet Mounting
- Others
On the basis of mounting technique, the global cryo-electron microscopy market is segmented into surface mounting, edge mounting, film emulsion mounting, rivet mounting, and others.
Application
- Biological Science
- Material Science
- Nanotechnology
- Lifesciences
- Medical
- Semiconductor
- Others
On the basis of application, the global cryo-electron microscopy market is segmented into, biological science, material science, nanotechnology, lifesciences, medical, semiconductor, others.
End User
- Research Laboratories and Institutes
- Forensic and Diagnostic Laboratories
- Pharmaceutical and Biotechnology Companies
- Contract Research Organization
- Others
On the basis of end user, the global cryo-electron microscopy market is segmented into research laboratories and institutes, forensic and diagnostic laboratories, pharmaceutical and biotechnology companies, contract research organization, others.
Distribution Channel
- Direct Tender
- Third Party Distribution
- Others
On the basis of distribution channel, the global cryo-electron microscopy market is segmented into direct tender, third party distribution, others.
Global Cryo-Electron Microscopy Market Regional Analysis/Insights
The global cryo-electron microscopy market is analyzed, and market size insights and trends are provided by country, product type, method type, nano formulations, technology, mounting technique, application, end user, and distribution channel, as referenced above.
Some countries covered in the global cryo-electron microscopy market are the U.S., Canada, France, U.K., Germany, Finland, Netherlands, Denmark, Sweden, Switzerland, Belgium, Spain, Rest of Europe, China, Japan, Australia, Singapore, India, South Korea, Taiwan, Rest of Asia-Pacific, Brazil, Saudi Arabia, Israel, South Africa, Rest of Middle East and Africa.
The U.S. in the North American region is expected to dominate due to the rising technological advancements in microscopy, and growing R&D investments and the launch of new products are boosting the market growth. France is expected to dominate due to the use of cryo-electron microscopy for biological studies in research institutes. The increasing usage of cryo-electron microscopes leads to the highest market in China due to the presence of various research institutes and therapeutic studies.
The country section of the report also provides individual market-impacting factors and changes in regulations in the market that impact the current and future trends of the market. Data points, such as new and replacement sales, country demographics, disease epidemiology, and import-export tariffs, are some of the major pointers used to forecast the market scenario for individual countries. In addition, the presence and availability of global brands and their challenges faced due to competition from local and domestic brands and the impact of sales channels are considered while providing forecast analysis of the country data.
Competitive Landscape and Global Cryo-Electron Microscopy Market Share Analysis
The global cryo-electron microscopy market and competitive landscape provide details by the competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points provided are only related to the companies' focus related to global cryo-electron microscopy market.
Some of the major players operating in the global cryo-electron microscopy market are Thermo Fisher Scientific Inc., Olympus Corporation, OPTIKA, Helmut Hund Gmbh, Labindia Instruments, JEOL Ltd., Leica Microsystems, Thermo Fisher Scientific Inc., KEYENCE CORPORATION., ZEISS International, Molecular Devices, LLC., Nikon Instruments Inc., Intertek Group plc, Caliber Imaging & Diagnostics, Lasertec Corporation, Thorlabs, Inc., Oxford Instruments, Hamamatsu Photonics K.K., NanoFocus AG, HORIBA, Ltd., Labomed, Inc., Creative Biostructure, Gatan, Inc., and Hitachi High-Tech Corporation among others.
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