Global Mixed Mode Chromatography Resin Market – Industry Trends and Forecast to 2031

Análise e tamanho do mercado de resina de cromatografia de modo misto

O mercado das resinas para cromatografia de modo misto está a sofrer avanços significativos, impulsionados pela adoção dos mais recentes métodos e tecnologias. Este crescimento é alimentado pelo aumento da utilização em diversos setores, como o biofarmacêutico, alimentos e bebidas e análise ambiental. A versatilidade e a eficiência das resinas de cromatografia de modo misto estão a impulsionar a expansão do mercado, com foco na melhoria dos processos de purificação e na obtenção de rendimentos mais elevados.

O tamanho global do mercado de resina de cromatografia de modo misto foi avaliado em 110,71 milhões de dólares em 2023 e deverá atingir 193,08 milhões de dólares até 2031, com um CAGR de 7,20% durante o período de previsão de 2024 a 2031. Além dos insights sobre cenários de mercado, tais como como valor de mercado, taxa de crescimento, segmentação, cobertura geográfica e grandes players, os relatórios de mercado com curadoria da Data Bridge Market Research também incluem análises especializadas aprofundadas, produção e capacidade da empresa representada geograficamente, layouts de rede de distribuidores e parceiros, análise detalhada e atualizada das tendências de preços e análise do défice da cadeia de abastecimento e da procura.

Âmbito do relatório e segmentação de mercado

Definição de mercado

A resina de cromatografia de modo misto contém ligantes com propriedades hidrofóbicas e iónicas, permitindo a interação simultânea com as proteínas com base na carga, hidrofobicidade e tamanho. Esta versatilidade permite a purificação eficiente de biomoléculas como proteínas, peptídeos e ácidos nucleicos. Proporciona maior seletividade e flexibilidade na separação de misturas complexas, tornando-se uma ferramenta valiosa na investigação biofarmacêutica e bioquímica.

Dinâmica do mercado da resina de cromatografia de modo misto

Motoristas

• Aumento da procura por produtos biofarmacêuticos

A crescente procura de produtos biofarmacêuticos, incluindo anticorpos monoclonais , vacinas e proteínas recombinantes, está a impulsionar o mercado das resinas para cromatografia de modo misto. As empresas biofarmacêuticas procuram técnicas de purificação eficientes para garantir uma elevada pureza e rendimento do produto. Por exemplo, a crescente produção de anticorpos monoclonais para fins terapêuticos necessita de processos de purificação robustos, onde as resinas de cromatografia de modo misto se destacam na obtenção do nível desejado de pureza e rendimento do produto, impulsionando assim o seu crescimento de mercado.

• Aumento da adoção de tecnologias de uso único

O aumento das tecnologias de utilização única em instalações de bioprocessamento está a impulsionar o mercado de resinas para cromatografia de modo misto. Estas resinas integram-se perfeitamente nos sistemas descartáveis, simplificando as operações e reduzindo os custos. Por exemplo, na produção de anticorpos monoclonais, os sistemas de cromatografia de utilização única que empregam resinas de modo misto reduzem drasticamente o tempo de preparação e eliminam a necessidade de validação de limpeza, aumentando a eficiência e a produtividade nas operações de bioprocessamento.

Oportunidades

• Expansão das Organizações de Fabrico por Contrato (CMOs)

O crescente setor de fabrico por contrato, especialmente nos produtos biofarmacêuticos, apresenta um caminho privilegiado para os fornecedores de resinas para cromatografia de modo misto. À medida que as Organizações de Fabrico por Contrato (CMOs) se esforçam por satisfazer a crescente procura, dão prioridade a soluções de purificação eficientes e económicas. Por exemplo, CMOs como a Catalent e a Lonza dependem cada vez mais de resinas de cromatografia de modo misto para agilizar as operações de bioprocessamento, sublinhando o papel fundamental destas resinas no apoio à expansão dos serviços de fabrico por contrato.

• Avanços na tecnologia de resinas para cromatografia

Continuous advancements in chromatography resin technology, such as the creation of innovative ligands and enhanced resin matrices, are driving the mixed mode chromatography resin market forward. For instance, the development of novel ligands with specific binding properties and improved resin matrices with higher binding capacities has enabled superior performance and scalability in biopharmaceutical purification processes, meeting the industry's evolving needs efficiently.

 Restraints/Challenges

• Complexity of Operation

The complexity of operating mixed-mode chromatography resins restricts their adoption, as users lacking specialized knowledge and experience find them challenging. This limitation hinders market growth by creating barriers to entry for potential users unfamiliar with the technology, diminishing the overall market potential for these chromatography resins.

• Column Packing Challenges

Column packing challenges hinder the mixed-mode chromatography resin market, with complexities arising from the intricate chemistry involved. These difficulties contribute to inconsistent column performance, discouraging adoption. This obstacle impacts the market's growth potential, impeding its widespread utilization within chromatography applications.

This market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Impact and Current Market Scenario of Raw Material Shortage and Shipping Delays

Data Bridge Market Research offers a high-level analysis of the market and delivers information by keeping in account the impact and current market environment of raw material shortage and shipping delays. This translates into assessing strategic possibilities, creating effective action plans, and assisting businesses in making important decisions. Apart from the standard report, we also offer in-depth analysis of the procurement level from forecasted shipping delays, distributor mapping by region, commodity analysis, production analysis, price mapping trends, sourcing, category performance analysis, supply chain risk management solutions, advanced benchmarking, and other services for procurement and strategic support.

Expected Impact of Economic Slowdown on the Pricing and Availability of Products

When economic activity slows, industries begin to suffer. The forecasted effects of the economic downturn on the pricing and accessibility of the products are taken into account in the market insight reports and intelligence services provided by DBMR. With this, our clients can typically keep one step ahead of their competitors, project their sales and revenue, and estimate their profit and loss expenditures.

Recent Development

• In September 2022, Purolite unveiled a strategic alliance with PharmNXT Biotech, aiming to introduce its Praesto agarose-based Protein A and Ion Exchange chromatography resins to South Korea and Singapore. This partnership seeks to bolster the distribution and availability of the Praesto range, specifically targeting the South Korean market
• In September 2022, Tosoh Bioscience LLC launched the Octave BIO Multi-Column Chromatography (MCC) system, tailored for advancing pre-clinical processes. Distinguished by its versatile modular design, this system accommodates various resins, enhancing flexibility and efficiency in chromatographic applications for biotherapeutic development
• In June 2022, Bio-Rad Laboratories, Inc. launched EconoFit Chromatography Column Packs, tailored to support screening experiments with an array of resin options. These packs include prepacked columns featuring mixed-mode, cation, and anion resins, offering researchers the flexibility to select optimal chemistry for diverse target molecules in screening studies
• In June 2022, Tosoh Bioscience GmbH introduced SkillPak 50 and 200 pre-packed columns, designed for the development of a spectrum of biopharmaceuticals, including antibody fragments, viruses, antibody-drug conjugates (ADCs), monoclonal antibodies, and oligonucleotides. These columns streamline the chromatographic process, enhancing efficiency and reproducibility in bioprocess development

Mixed Mode Chromatography Resin Market Scope

The market is segmented on the basis of technique, end use and application. The growth amongst these segments will help you analyse meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Technique

• Ion Exchange – Hydrophobic
• Hydroxyapatite

 End Use

• Pharmaceutical and Biotechnology

 Application

• Antibodies Production
• Vaccine Production
• Non-Antibody Proteins
• Antibody-Drug Conjugate
• Separation of Low Molecular Weight Impurities

Mixed Mode Chromatography Resin Market Regional Analysis/Insights

The market is analysed and market size insights and trends are provided by technique, end use and application industry as referenced above.

The countries covered in the market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America is expected to dominate the mixed mode chromatography resin market, propelled by increased investments in innovative research activities. The region benefits from the emergence of advanced technologies in various industries, further fueling market growth and driving adoption of these resins for diverse applications.

Asia-Pacific is expected to grow at the highest growth rate in the mixed mode chromatography resin market, driven by government initiatives supporting pharmaceutical and biotechnology industries. Investments and advancements in this region foster innovation, propelling the adoption of mixed mode chromatography resin for diverse bioprocessing applications.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Competitive Landscape and Mixed Mode Chromatography Resin Market Share Analysis

The market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to market.

Some of the major players operating in the market are:

• Bio-Rad Laboratories, Inc. (U.S.)
• HOYA Corporation (Japan)
• Tosoh India Pvt. Ltd. (Japan)
• Merck KGaA (Germany)
• Danaher Corporation (U.S.)
• Purolite (U.S.)
• General Electric Company (U.S.)
• Sartorius AG (Germany)
• Thermo Fisher Scientific, Inc. (U.S.)
• Geno Technology Inc. (U.S.)
• Sepragen Corporation (U.S.)
• Bio-Works (Sweden)
• DuPont (U.S.)
• Cytiva (U.S.)
• Sunresin New Materials Co.Ltd. (China)
• Anatrace Products, LLC (U.S.)
• YMC Process Technologies (Japan)

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