Applications of Cryo-Electron Microscopy in Understanding Neurodegenerative Diseases

The global cryo-electron microscopy market is poised for significant growth in the forecast period. Factors such as the presence of numerous market players and the availability of advanced services contribute to market expansion. Manufacturers' focus on research and development activities to introduce innovative services further drives market growth. Additionally, the increasing research in nanotechnology fuels the demand for cryo-electron microscopy.

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Data Bridge Market Research analyses that the Global Cryo-Electron Microscopy Market is growing with a CAGR of 8.7% in the forecast period of 2023 to 2030 and market value of 2022 was USD 786.55 million and expected to reach USD 1,533.08 million by 2030. Advancements in Cryo-EM technology, such as improvements in imaging resolution and data quality, have expanded the applications of Cryo-EM in structural biology, drug discovery, and material science. These technological advancements have increased the demand for Cryo-EM instruments and services, driving the growth of the Cryo-Electron Microscopy market.

Key Findings of the Study

The increasing investment in research and development (R&D) is expected to drive the market's growth rate

The increasing investment in research and development (R&D) is a significant driver of the Cryo-Electron Microscopy (Cryo-EM) market. Governments, academic institutions, and private organizations are allocating substantial funding to support R&D activities, particularly in the field of structural biology. This financial support enables the development of innovative Cryo-EM technologies, such as improved imaging systems and advanced data analysis software. The emphasis on R&D investment fosters technological advancements, enhances the capabilities of Cryo-EM instruments, and expands their applications in various scientific disciplines. This drives the growth of the Cryo-EM market as researchers and scientists strive to explore new frontiers in understanding the structure and function of biological molecules at the atomic level.

Report Scope and Market Segmentation

Segment Analysis:

The global cryo-electron microscopy market is segmented into product type, method type, nano formulations, technology, mounting technique, application, end user, and distribution channel.

• On the basis of product type, the global cryo-electron microscopy market is segmented into hardware and software. In 2023, the hardware segment is expected to dominate the global cryo-electron microscopy market with a 92.00% market share due to its essential role in the imaging process. Cryo-electron microscopy (cryo-EM) requires advanced hardware components, such as electron microscopes and detectors, to capture high-resolution images of biological samples in the forecast period of 2023 to 2030

In 2023 the hardware segment dominate the global cryo-electron microscopy market

In 2023 the hardware segment dominate the global cryo-electron microscopy market with the market share of 92.00% owing to its crucial role in the imaging process. Cryo-electron microscopy (cryo-EM) relies on sophisticated hardware components, such as electron microscopes and detectors, to capture high-resolution images of biological samples. Ongoing advancements in cryo-EM hardware, such as increased imaging speeds and enhanced sensitivity, further strengthen its position in the market as a precise and powerful tool for detailed biological imaging and research in the forecast period of 2023 to 2030.

• On the basis of method type, the global cryo-electron microscopy market is segmented into electron crystallography, single particle analysis, cryo-electron tomography, and others. In 2023, the single particle analysis segment is expected to dominate the global cryo-electron microscopy market with a 42.96% market share due to its wide range of applications in structural biology research. Cryo-electron microscopy (cryo-EM) single particle analysis allows researchers to study the three-dimensional structure of individual biological molecules. Its ability to analyze complex and heterogeneous samples with high resolution makes it a preferred technique for drug development, understanding disease mechanisms, and advancing scientific knowledge in the forecast period of 2023 to 2030.

In 2023, the single particle analysis segment is expected to dominate the global cryo-electron microscopy market

In 2023, the single particle analysis segment is expected to dominate the global cryo-electron microscopy market with the market share of 42.96% due to their vital role in delivering therapeutic agents and genetic material to cells. Cryo-electron microscopy (cryo-EM) enables researchers to visualize these nanoparticles with high resolution, providing valuable insights into their structure and behavior. As there is a rising interest in developing advanced drug delivery systems and gene therapies, the demand for cryo-EM is increasing to accurately characterize lipid nanoparticle formulations for effective and targeted treatments in the forecast period of 2023 to 2030.

• On the basis of nano formulations, the global cryo-electron microscopy market is segmented into lipid nanoparticle formulations (LNFS), metal oxide formulations, metal formations, others. In 2023, lipid nanoparticle formulations (LNFS) segment is expected to dominate the market global cryo-electron microscopy market with a 37.08%market share due to their crucial role in delivering therapeutic agents and genetic material to cells. Cryo-electron microscopy (cryo-EM) allows researchers to visualize these lipid nanoparticles at high resolution, providing insights into their structure and behavior. The growing interest in developing innovative drug delivery systems and gene therapies further drives the demand for cryo-EM in characterizing lipid nanoparticle formulations in the forecast period of 2023 to 2030.
• On the basis of technology, the global cryo-electron microscopy market is segmented into transmission electron microscopy (TEM), scanning electron microscopy (SEM), and nuclear magnetic resonance (NMR) microscopy. In 2023, the transmission electron microscopy (TEM) segment is expected to dominate the market with a 50.65% market share due to its widespread application in high-resolution imaging of biological samples and materials. TEM allows researchers to study the ultrastructure of cells, viruses, and nanoparticles, providing valuable insights into their morphology and composition. Its ability to capture detailed images at nanoscale resolution makes TEM a vital tool in various scientific fields, driving its dominance in the cryo-electron microscopy market in the forecast period of 2023 to 2030.
• On the basis of mounting technique, the global cryo-electron microscopy market is segmented into surface mounting, edge mounting, film emulsion mounting, rivet mounting, and others. In 2023, surface mounting segment is expected to dominate the market with a 34.60% market share due to its crucial role in sample preparation for cryo-electron microscopy. This technique involves mounting the biological sample on a grid and rapidly freezing it to preserve its native structure. Surface Mounting allows researchers to study biomolecules, viruses, and cellular structures in their natural state, providing valuable insights into their functions and interactions at high resolution, driving its dominance in the market in the forecast period of 2023 to 2030.
• On the basis of application, the global cryo-electron microscopy market is segmented into biological science, material science, nanotechnology, lifesciences, medical, semiconductors, and others. In 2023, biological science segment is expected to dominate the market with a 26.47% market share because cryo-electron microscopy is extensively used to study biological structures and processes at the molecular level. It allows researchers to visualize complex biomolecules, proteins, viruses, and cellular components in their native state, providing invaluable insights into their functions and interactions. As a result, the application of cryo-electron microscopy in biological science drives its dominance in the market, shaping cutting-edge research and advancements in the field in the forecast period of 2023 to 2030
• On the basis of end user, the global cryo-electron microscopy market is segmented into research laboratories and institutes, forensic and diagnostic laboratories, pharmaceutical and biotechnology companies, contract research organization, and others. In 2023, the research laboratories and institutes segment is expected to dominate the global cryo-electron microscopy market with a 34.56% market share because cryo-electron microscopy is a powerful tool extensively used by researchers to study the structures of various biological molecules, viruses, and cellular components. It enables detailed visualization of complex biomolecules in their native state, providing crucial insights into their functions and interactions. in the forecast period of 2023 to 2030.
• On the basis of distribution channel, the global cryo-electron microscopy market is segmented into direct tender, third party distribution, and others. In 2023, the direct tender segment is expected to dominate the global cryo-electron microscopy market with a 51.96% market share due to they involve direct procurement from manufacturers, providing advantages such as competitive pricing, better product availability, and customization options. Research institutions and academic facilities often prefer direct tenders to ensure seamless access to cutting-edge cryo-electron microscopy systems and related equipment. This procurement approach allows them to stay at the forefront of scientific research and maximize the potential of cryo-electron microscopy in their studies.in the forecast period of 2023 to 2030.

Major Players

Data Bridge Market Research recognizes the following companies as the major global cryo-electron microscopy market players in global cryo-electron microscopy market  are Thermo Fisher Scientific Inc. (U.S.) Olympus Corporation (Japan) OPTIKA (Italy) Helmut Hund Gmbh (Germany) Labindia Instruments (India) JEOL Ltd. (Japan) Leica Microsystems (Germany) KEYENCE CORPORATION (Japan) ZEISS International (Germany)

Market Development

• In 2022, Thermo Fisher Scientific Inc., the world leader in science service, introduced the Thermo Scientific Glacios 2 Cryo-Transmission Electron Microscope (Cryo-TEM), a powerful microscope with new automation and high-resolution imaging capabilities designed to help cryo-EM researchers of varying experience levels accelerate structure-based drug discovery. Customers may be able to speed up the pace of research for debilitating disorders such as Alzheimer's, Parkinson's, and Huntington's diseases, as well as cancer and gene mutation research, using this advanced, fast, and cost-effective method for drug design. This has aided the company in expanding its global market presence.
• In 2022, Hitachi High-Tech Corporation announced the release of the AFM100 Pro High-Sensitivity Scanning Probe Microscope System, a high-end scanning probe microscope (AFM*1/SPM*2) with a newly developed high-sensitivity optical head that develops sensitivity when measuring physical properties and allows measurement at atomic and molecular scales. This has aided the company in expanding its global presence.

Regional Analysis

Geographically, the countries covered in the cryo-electron microscopy market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America

As per Data Bridge Market Research analysis:

Asia-Pacific is the dominant region in cryo-electron microscopy market in the forecast period 2023 - 2030

Asia-Pacific is dominating because of its advanced infrastructure for informatics research and development and rising demand for genomic studies. Other factors contributing to the region's high share include the presence of advanced infrastructure, rising demand for genomic studies, and rising government funding.

North America is estimated to be the fastest-growing region in cryo-electron microscopy market in the forecast period 2023 - 2030

North America is expected to dominate the global cryo-electron microscopy market due to microscopy technology advancements, rising R&D investments and the introduction of new products are driving market growth.

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