Marché des thérapies à base de cellules tueuses naturelles (NK) en Asie-Pacifique – Tendances et prévisions du secteur jusqu’en 2030

Analyse et perspectives du marché des thérapies à base de cellules tueuses naturelles (NK) en Asie-Pacifique

Le marché des thérapies à base de cellules tueuses naturelles (NK) en Asie-Pacifique comprend des caractéristiques telles que le besoin croissant de meilleures options thérapeutiques qui auront un impact sur le lancement d'un nouveau produit par les fabricants sur le marché, augmentant sa demande ainsi que l'augmentation des investissements en R&D conduisant à la croissance du marché. Actuellement, diverses études de recherche sont en cours qui devraient créer un avantage concurrentiel pour les fabricants pour développer de nouvelles thérapies innovantes à base de cellules NK, ce qui devrait offrir diverses autres opportunités de croissance du marché. Cependant, le manque de spécificité et la faible survie in vivo des cellules, ainsi que le coût élevé associé aux thérapies devraient freiner la croissance du marché au cours de la période de prévision.

Le marché des thérapies par cellules tueuses naturelles (NK) en Asie-Pacifique est favorable et vise à réduire la progression de la maladie. Data Bridge Market Research analyse que le marché des thérapies par cellules tueuses naturelles (NK) en Asie-Pacifique connaîtra une croissance de 45,2 % au cours de la période de prévision de 2023 à 2030.

Le rapport sur le marché des thérapies par cellules tueuses naturelles (NK) en Asie-Pacifique fournit des détails sur la part de marché, les nouveaux développements, l'analyse du pipeline de produits, l'impact des acteurs du marché national et local, analyse les opportunités en termes de poches de revenus émergentes, les changements dans la réglementation du marché, les approbations de produits, les décisions stratégiques, les lancements de produits, les expansions géographiques et les innovations technologiques sur le marché. Pour comprendre l'analyse et le scénario du marché, contactez-nous pour un briefing d'analyste, notre équipe vous aidera à créer une solution d'impact sur les revenus pour atteindre votre objectif souhaité.

Market Definition

Natural killer (NK) cells are large granular lymphocytes that have the ability to quickly respond to a pathological challenge. They are important components of the innate immune system and play an important role in generating an immune response against malignancies and infectious diseases caused by viral pathogens. They have been recognized to induce the direct killing of targeted cells involving cancer cells. They have the ability to recognize the multitude of infected cells without being dependent on a single antigen-expressing cell.

NK cells secrete cytokines and chemokines that recruit other immune cells such as T cells and B cells, which enhances the immune response against the tumor cells. As NK cells do not express T cell receptors, they induce a low risk of graft-versus-host disease. Moreover, iPSC cell lines derived NK cell therapy that is CAR-NK therapy overcomes the need for a long and complex manufacturing process that allows patients with aggressive tumors to afford tumor treatment as soon as possible. Along with this iPSC derived NK cells can be infused repeatedly, which enhances the immune response with dose regulation.

Asia-Pacific Natural Killer (NK) Cell Therapeutics Market Dynamics

This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:

DRIVERS

• Increase in Patient Population with Chronic Diseases

Chronic diseases are diseases that generally occur in older adults that can be controlled but not cured such as heart disease, arthritis, diabetes, stroke, or cancer. They are a worldwide healthcare problem concern. The change in lifestyle along with physical inactivity, unhealthy diet, and tobacco use is increasing the burden of chronic diseases all over the world.

An increasing number of patients population with chronic diseases led the scientist and researchers to work on a new innovative therapeutic approach so as to provide patients with the best curative treatment option, which can be achieved by using NK cell therapy that has the potential to generate a strong immune response and has the anti-tumor capability as well.

• Rise in Awareness about Immunotherapies

As cancer is a devastating disease and available treatment options may cause the reoccurrence of tumors, the need for the best therapeutic approach is increasing day by day. Immunotherapies have attracted a lot of attention in recent years for the treatment of various types of malignancies. Among the immunotherapies, CAR–T cell therapies have been studied and were used as well but have several limitations, which led to the development of NK cell therapies. As a drug based on an NK cell therapeutic approach has not been approved yet, it thus needs to raise awareness among the population.

This is why several organizations and market players are launching a campaign to enhance awareness regarding NK cell therapies.

OPPORTUNITY

•  Strategic Initiatives by Market Players

Various strategic initiatives are adopted by market players which involve expansion, acquisition, and collaboration among others. These initiatives help them to increase the company’s product portfolio leading to market expansion and hence enhancing the product demand among customers, which ultimately leads the players to earn maximum revenue.

As the demand for effective and affordable NK cell immunotherapy is increasing worldwide, these strategic initiatives are taken by top market players aimed at enhancing business operations and earning more profitability in the market.

RESTRAINT/CHALLENGE

• Lack of Specificity and Poor In Vivo Survival of the cells

Lack of specificity and poor in-vivo survival of NK cells poses a challenge in front of manufacturers dealing in the market. The lack of specificity of NK cells leads to targeting the wrong cells, which can lead to ineffective treatment. Along with this, the lack of specificity and poor in-vivo survival of NK cells also reduces the therapeutic effect of administered NK cell therapy.

Such problems decrease the credibility of therapy used in clinical trials and pose a challenge in front of manufacturers while getting approval.

Recent Developments

• In January 2022, Takeda acquired Adaptate biotherapeutics to develop novel gamma delta (γδ) T cell engager therapies targeting solid tumors. Through the acquisition, Takeda will obtain Adaptate’s antibody-based γδ T cell engager platform, including pre-clinical candidate and discovery pipeline programs. Adaptate’s γδ T cell engagers are designed to specifically modulate γδ T cell-mediated immune responses at tumor sites while sparing damage to healthy cells. This acquisition helped the company to focus on R&D.
• In December 2021, Nektar Therapeutics announced phase 1b data for novel T regulatory cell stimulator NKTR-358 (LY3471851) in patients with atopic dermatitis. NKTR-358 is designed to treat autoimmune and inflammatory conditions by correcting the immune system imbalance that results from increased levels of inflammatory T cells and reduced numbers and impaired function of immune regulating Treg cells. This has helped the company to focus on R&D for further phases.

Asia-Pacific Natural Killer (NK) Cell Therapeutics Market Scope

The Asia-Pacific natural killer (NK) cell therapeutics market is segmented into five notable segments based on therapeutics, approaches, application, end-user, and distribution channel. The growth among these segments will help you analyze niche pockets of growth and strategies to approach the market and determine the core application areas and the difference in the target markets.

Therapeutics

• NK Cell Therapies
• NK Cell Directed Antibodies

Based on therapeutics, the market is segmented into NK cell therapies and NK cell directed antibodies.

Approaches

• Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)
• Bispecific Antibodies

Based on approaches, the market is segmented into antibody-dependent cell-mediated cytotoxicity (ADCC) and bispecific antibodies.

Application

• Cancer
• Immunoproliferative Disorders
• Acute Infectious Diseases
•  Gastrointestinal Diseases
• Others

Based on application, the market is segmented into cancer, immunoproliferative disorders, acute infectious diseases, gastrointestinal diseases, and others.

End User

• Research & Academic Institutes
• Hospitals
•  Specialty Clinics

Based on end user, the market is segmented into hospitals, specialty clinics, and research & academic institutes.

Distribution Channel

• Hospital Pharmacies
•  Direct Tender
•  Others

Based on distribution channel, the market is segmented into hospital pharmacies, direct tender, and others.

Asia-Pacific Natural Killer (NK) Cell Therapeutics Market Regional Analysis/Insights

The Asia-Pacific natural killer (NK) cell therapeutics market is categorized into five notable segments: therapeutics, approaches, application, end-user, and distribution channel.

The countries covered in this market report are China, Japan, India, South Korea, Singapore, Thailand, Malaysia, Australia, Philippines, Indonesia, and the rest of Asia-Pacific.

Japan dominates the Asia-Pacific region due to rising awareness of regular health check-ups.

The country section of the report also provides individual market-impacting factors and changes in regulation in the market domestically that impact the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, regulatory acts, and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, the presence and availability of Asia-Pacific brands and their challenges faced due to large or scarce competition from local and domestic brands, and the impact of sales channels are considered while providing forecast analysis of the country data.

Competitive Landscape and Asia-Pacific Natural Killer (NK) Cell Therapeutics Market Share Analysis

Le paysage concurrentiel du marché des thérapies par cellules tueuses naturelles (NK) en Asie-Pacifique fournit des détails sur les concurrents. Les détails inclus sont la présentation de l'entreprise, les finances de l'entreprise, les revenus générés, le potentiel du marché, les investissements en R&D, les nouvelles initiatives du marché, la présence en Asie-Pacifique, les sites et installations de production, les capacités de production, les forces et les faiblesses de l'entreprise, le lancement du produit, la largeur et l'étendue du produit et la domination des applications. Les points de données ci-dessus fournis ne concernent que l'orientation des entreprises par rapport au marché.

Certains des principaux acteurs opérant sur le marché des thérapies à base de cellules tueuses naturelles (NK) en Asie-Pacifique sont Merck KGaA, Bristol-Myers Squibb Company, Glycostem, Sanofi, EMERcell, Phio Pharmaceuticals, Affimed GmbH, Multimmune GmbH et Takeda Pharmaceutical Company Limited.

SKU-56950