- In January 2024, AM-Pharma B.V. has initiated a Phase 2 clinical study, treating the first patients with ilofotase alfa to prevent cardiac surgery-associated renal damage (CSA-RD), a crucial step towards validating the compound's potential and advancing its development, ultimately benefiting the company by potentially expanding its therapeutic applications and market reach
- In October 2023, AM-Pharma B.V. has reported positive Phase 1b clinical results for ilofotase alfa as a potential enzyme replacement therapy in adult hypophosphatasia (HPP) patients. This milestone demonstrates the compound's efficacy and safety, potentially expanding its market and therapeutic applications, benefiting the company's growth and development
- In September 2023, AM-Pharma B.V. has updated its clinical strategy for ilofotase alfa, aiming to use the compound as a preventive treatment for Cardiac Surgery-Associated Renal Damage (CSA-RD) and as an enzyme replacement therapy for hypophosphatasia (HPP). These developments could significantly expand the company's market and therapeutic opportunities
- In July 2021, AstraZeneca has finalized its acquisition of Alexion Pharmaceuticals, Inc., marking its entry into rare disease medicines. This move enhances AstraZeneca's scientific presence in immunology and allows for continued innovation in rare disease treatments, leveraging Alexion's complement-biology platform and pipeline. This acquisition represents a significant growth opportunity for AstraZeneca, addressing the unmet medical needs of patients with rare diseases
