An increase in older adults will be accompanied by increase in the number of patients suffering from neurological disease. Neurologic disorders such as stroke, neuropathy, Alzheimer's disease, and Parkinson's disease are more common in the elderly population. Geriatrics make up a significant portion of the overall patient pool due to their increased susceptibility. According to the WHO, the global population of people aged 60 and above was 962 million in 2017 and is expected to reach 2.1 billion by 2050. According to World Population Prospects (2019 Revision), by 2050, one in every four people in Europe and Northern America will be 65 or older. As a result, the growing geriatric population has increased the demand for nerve repair biomaterials for the treatment of neuropathy.
According to Data Bridge Market Research the Nerve Repair Biomaterials Market accounted for USD 7.44 billion in 2021, and expected to reach USD 21.99 billion by 2029. The market is expected to grow with a CAGR of 14.50% in the forecast period of 2022 to 2029.
“Technological Advancements in Nerve Conduits is Facilitate Market Growth”
One of the most promising treatments for peripheral nerve injuries has been identified as nerve conduits. Existing nerve conduits must balance mechanical strength and biocompatibility. As technology advances, a multi-nozzle additive-lathe 3D bioprinting technology is used to fabricate a bilayered nerve conduit. The printing materials are gelatin methacrylate (GelMA)-based inner layer cellularized with bone marrow mesenchymal stem cells and GelMA (ethylene glycol) diacrylate (PEGDA)-based outer layer. Adjusting the degree of methacryloyl substitution and the concentration of GelMA resulted in high viability and extensive morphological spreading of BMSCs encapsulated in the inner layer. The addition of PEGDA resulted in the outer layer having a high mechanical performance. The performance of the bilayered nerve conduits was evaluated using in vitro PC12 cell culture. PC12 cells attached to cellularized bilayered nerve conduits had a cell density that was more than four times that of acellular bilayered nerve conduits. Furthermore, the growth rate of PC12 cells attached to cellularized bilayered nerve conduits was nine times that of acellular bilayered nerve conduits. As a result, these findings show that additive-lathe 3D bioprinting of BMSCs embedded bilayered nerve conduits has a high potential for facilitating peripheral nerve repair.
What restraints the growth of Nerve Repair Biomaterials Market?
“Disadvantages Associated with Natural-Based Biomaterials for Peripheral Nerve Injury Repair Are Expected to Hamper the Market's Growth”
The degradation kinetics of the substrate must be compatible with the regeneration timing of the specific tissue for which it is used. Ideally, the scaffold should be incorporated into the surrounding tissue and gradually replaced by the extracellular matrix and cells to restore tissue functionality. For instance, too rapid conduit degradation can cause an inflammatory response, resulting in suboptimal nerve regeneration. When nerve repair is complete, conduits should ideally be completely resorbed. As a result, the ideal degradation rate for a conduit should be faster at the proximal stump and gradually decreasing over distance, with a slow degradation rate near the distal end. As a result, the disadvantages associated with natural-based biomaterials for peripheral nerve injury repair are expected to impede market growth.
Segmentation: Nerve Repair Biomaterials Market
The nerve repair biomaterials market is segmented on the basis of type, application and end use.
- On the basis of product, the nerve regeneration and repair market is segmented into neurostimulation and neuromodulation devices and biomaterials.
- On the basis of indication, the nerve regeneration and repair market is segmented into failed back surgery syndrome, Parkinson's disease, urinary incontinence, epilepsy, gastroparesis, nerve repair, grafting.
- On the basis of application, the nerve regeneration and repair market is segmented into neurostimulation and neuromodulation surgeries, neurorrhaphy, nerve grafting, and stem cell therapy.
- On the basis of end-user, the nerve regeneration and repair market is segmented into hospitals and clinics, ambulatory surgical centers.
Regional Insights: North America is expected to dominate the Nerve Repair Biomaterials Market
Asia-Pacific is expected to dominate the market due to the increase in number of patients suffering from chronic diseases in the region.
- In addition, the North America region is likely to register highest growth rate during the forecast period of 2022 to 2029 because of the region's well-developed healthcare industry and the presence of leading medical diagnostics manufacturers. Incidences of peripheral nerve injuries are increasing, as is the prevalence of neurological disorders, and proper repayment guidelines. There is a large and growing burden of noncommunicable neurological disorders in the United States, with up to a 5-fold variation in the burden of and trends in specific neurological disorders across states.
To know more about the study visit, https://www.databridgemarketresearch.com/reports/global-nerve-regeneration-and-repair-market
Recent Developments in Nerve Repair Biomaterials Market
- In 2020, Medtronic received CE Mark for its InterStimTM Micro neurostimulator and InterStimTM SureScanTM MRI leads. In Europe, the technologies are approved for commercial sale and clinical use, and they provide full-body MRI scan-eligible and lifestyle-friendly options.
The Prominent Key Players Operating in the Nerve Repair Biomaterials Market Include:
- Stryker (U.S.)
- Collagen Matrix, Inc. (U.S.)
- Axogen Corporation. (U.S.)
- Checkpoint Surgical, Inc. (US)
- Polyganics (Netherlands)
- Synovis Micro Companies Alliance, Inc. (U.S.)
- Medtronic (U.S.)
- Boston Scientific Corporation (U.S.)
- Abbott (U.S.)
- LivaNova PLC (U.K.)
- Cyberonics, Inc. (U.S.)
- Nuvectra. (U.S.)
- OrthoMed, Inc. (U.S.)
- AxoGen, Inc. (U.S.)
- Baxter International, Inc. (U.S.)
- Integra LifeSciences (U.S.)
- NeuroPace, Inc. (U.S.)
- Soterix Medical, Inc. (U.S.)
- Nevro Corp (U.S.)
- Synapse Biomedical, Inc. (U.S.)
- KeriMedical (Switzerland)
- BioWave Corporation (U.S.)
- NeuroSigma (U.S.)
Above are the key players covered in the report, to know about more and exhaustive list of nerve repair biomaterials market companies contact, https://www.databridgemarketresearch.com/contact
Research Methodology: Global Nerve Repair Biomaterials Market
Data collection and base year analysis are done using data collection modules with large sample sizes. The market data is analyzed and estimated using market statistical and coherent models. In addition, market share analysis and key trend analysis are the major success factors in the market report. The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market, and primary (industry expert) validation. Apart from this, data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Company Market Share Analysis, Standards of Measurement, global vs Regional and Vendor Share Analysis. Please request analyst call in case of further inquiry.
