Global Prokaryotic Expression Systems Market, By Host Type (Archaea, Bacillus Subtilis, Corynebacterium Glutamicum, Escherichia Coli Systems, Pseudomonas Alcaligenes), Product (Amino Acids, Biopolymers, Ascorbic Acids, Pigments, Enzymes, Antibiotics, Lipases, Instruments, Competent Cells, Reagents, Expression Vectors, Services), Application (Research Applications, Therapeutic Proteins, Industrial Proteins), End User (Academic Research, Biotechnological Companies, Pharmaceuticals, Contract Research Organizations) – Industry Trends and Forecast to 2029.
Prokaryotic Expression Systems Market Analysis and Size
The prokaryotic system is the most widely used system for protein overproduction, both in the laboratory and in industry. This system is primarily based on the bacteria E. coli, though Bacillus species are increasingly being used. The prokaryotic system allows for the rapid production of large quantities of recombinant proteins. The use of these microorganisms is facilitated by a simple and inexpensive bacterial cell culture and well-known transcription and translation mechanisms. The prokaryotic system also has the advantage of being simple to modify genetically and having a large number of bacterial mutants available.
Data Bridge Market Research analyses that the prokaryotic expression systems market which was USD 294.49 million in 2021, is expected to reach USD 808.17 million by 2029, at a CAGR of 13.45% during the forecast period 2022 to 2029. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.
Prokaryotic Expression Systems Market Scope and Segmentation
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Report Metric
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Details
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Forecast Period
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2022 to 2029
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Base Year
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2021
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Historic Years
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2020 (Customizable to 2014 - 2019)
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Quantitative Units
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Revenue in USD Million, Volumes in Units, Pricing in USD
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Segments Covered
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Type (Pure Silica Fiber, Polycrystalline Fiber, Polymer Optical), Fiber Type (Single-Mode Optical Fiber and Multimode Optical Fiber), Usage (Re-usable, Disposable), End User (Hospitals, Ambulatory Surgical Centers, Specialty Clinics, Contract Research Organization (CRO), Diagnostic Laboratories), Application (Image Transmission, Laser Signal Delivery, Illumination, Laser soldering, Fiber Optic Confocal Scanning)
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Countries Covered
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U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
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Market Players Covered
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Agilent Technologies, Inc. (U.S.), Merck KGaA (Germany), Bio-Rad Laboratories, Inc. (U.S.), QIAGEN (Germany), Promega Corporation (U.S.), Thermo Fischer Scientific, Inc. (U.S.), Takara Bio Inc. (Japan), GenScript (U.S.), Lonza (Switzerland), New England Biolabs (U.S.), Oxford Expression Technology (U.K.), LifeSensors Inc. (U.S.), Proteogenix (France), Synthetic Genomics Inc. (U.S.), Peak Proteins Ltd (U.K.), Sino Biological Inc. (China), ARTES Biotechnology GmbH (Germany)
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Market Opportunities
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Market Definition
The prokaryotic expression system is one of the most commonly used genetic engineering approaches for the expression and secretion of exogenous target genes. The vector and the expression host are the basic elements of any expression system. The prokaryotic system is the most widely used system for protein overproduction, both in the laboratory and in industry. This system is primarily based on the bacteria E. coli, though Bacillus species are increasingly being used.
Global Prokaryotic Expression Systems Market Dynamics
Drivers
- Rising use of E. coli bacteria
The market is expanding due to the large-scale production of a protein using E. coli bacteria, as E. coli is the most commonly used artificial expression host. E. coli is widely used because of its genomic and physiological sequencing system, which is responsible for simplifying the cloning procedure and making the E. coli host the most popular in the pharmaceutical industry. Furthermore, this process is responsible for increasing the binding strength of promoter region 7 and aiding in transcription. Furthermore, prokaryotic expression is critical in the pharmaceutical and biotechnology industries. These factors are expected to boost growth.
- Research and development activities to bolster the growth
The market for prokaryotic expression systems is dominated by the research and applications. The segment's growth is attributed to the large-scale application and benefits such as prokaryotes' rapid growth and use in molecular biology, genetics, and biochemistry research. Prokaryotic organisms are essential to all living organisms and play an important role in recycling nutrients by decomposing dead organisms. As a result of this, they are widely used in research as healthy bacteria. Furthermore, studies are being conducted to improve the activity of prokaryotic in the pharmaceutical and biotechnology industries in order to improve the action of pharmaceutical drugs. However, the current trend of moving genetic parts from prokaryotic to eukaryotic for the corresponding DNA-binding sequencing by E. coli is likely to boost the market growth.
Opportunities
- Technological development to create opportunities
Increasing advancement in genomic sequences along with technological advancement for instance, in April 2020, Bio-Rad laboratories, Inc., a leading life science research organisation based in the United States, acquired Celsee, Inc. to provide instruments and consumables for the isolation, detection, and analysis of single cells.in proteomics which will further boost various opportunities for the growth of the prokaryotic expression systems market in the above mentioned forecast period.
Restraints/Challenges
- High cost of protein expression
High barrier on the entry of the new organisation along with high cost of protein expression reagents will obstruct the market's growth rate. Limited disease awareness, high product costs, poor economic conditions, and a lack of favourable insurance systems all limit the adoption of prokaryotic expression systems products in developing regions around the world.
This prokaryotic expression systems market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the prokaryotic expression systems market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Recent developments
- In April 2020, US-based leading life science research organization, Bio-Rad laboratories, Inc., acquired Celsee, Inc. to offers instruments and consumables for the isolation, detection, and analysis of single cells.
Global Prokaryotic Expression Systems Market Scope
The prokaryotic expression systems market is segmented on the basis of host type, product, application and end user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Host Type
- Archaea
- Bacillus Subtilis
- Corynebacterium Glutamicum
- Escherichia Coli Systems
- Pseudomonas Alcaligenes
Product
- Amino Acids
- Biopolymers
- Ascorbic Acids
- Pigments
- Enzymes
- Antibiotics
- Lipases
- Instruments
- Competent Cells
- Reagents
- Expression Vectors
- Services
Application
- Research Applications
- Therapeutic Proteins
- Industrial Proteins
End User
- Academic Research
- Biotechnological Companies
- Pharmaceuticals
- Contract Research Organizations
Prokaryotic Expression Systems Market Regional Analysis/Insights
The prokaryotic expression systems market is analysed and market size insights and trends are provided by country, host type, product, application and end user as referenced above.
The countries covered in the prokaryotic expression systems market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
North America dominates the prokaryotic expression systems market owing to factors such as continuous advancements to genome sequencing and innovations to proteomics in countries such as US and Canada.
Asia-Pacific is expected to grow at the highest growth rate in the forecast period of 2022 to 2029 due to the factors ascribing to the growth of the region are cumulative research studies carried out by the market players and growing investment in research and development activities gene expression is likely to motivate the market growth.
The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.
Healthcare Infrastructure Growth Installed base and New Technology Penetration
The prokaryotic expression systems market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for prokaryotic expression systems market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the prokaryotic expression systems market. The data is available for historic period 2010-2020.
Competitive Landscape and Prokaryotic Expression Systems Market Share Analysis
The prokaryotic expression systems market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to prokaryotic expression systems market.
Some of the major players operating in the prokaryotic expression systems market are:
- Agilent Technologies, Inc. (U.S.)
- Merck KGaA (Germany)
- Bio-Rad Laboratories, Inc. (U.S.)
- QIAGEN (Germany)
- Promega Corporation (U.S.)
- Thermo Fischer Scientific, Inc. (U.S.)
- Takara Bio Inc. (Japan)
- GenScript (U.S.)
- New England Biolabs (U.S.)
- Oxford Expression Technology (U.K.)
- LifeSensors Inc. (U.S.)
- Lonza (Switzerland)
- Proteogenix (France)
- Synthetic Genomics Inc. (U.S.)
- Peak Proteins Ltd (U.K.)
- Sino Biological Inc. (China)
- ARTES Biotechnology GmbH (Germany)
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