Global P2X7 Receptor Antagonists Market
Market Size in USD Billion
CAGR :
% 
 Forecast Period |
2024 –2031 |
 Market Size (Base Year) |
USD 148.53 Million |
 Market Size (Forecast Year) |
USD 544.17 Million |
 CAGR |
% |
| Major Markets Players |
Global P2X7 Receptor Antagonists Market, By Drug Product (AKP-23494954/RQ-00466479, EVT 401, GSK1482160, JNJ-55308942, JNJ-54175446, Others), Application (Central Nervous System Disorders, Immunological Disorders, Others), End User ( Hospitals, Ambulatory Surgical Center, Pharmaceutical and Biotechnology Companies, Others) – Industry Trends and Forecast to 2031.
P2X7 Receptor Antagonists Market Analysis and Size
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Data Bridge Market Research analyzes that the P2X7 receptor antagonists market, which was USD 148.53 million in 2023, is likely to reach USD 544.17 million by 2031 and is expected to undergo a CAGR of 17.6% during the forecast period. “AKP-23494954/RQ-00466479” dominates the drug product segment of the P2X7 Receptor Antagonists market due to the growing demand for better methods for treatment in patients. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.
Report Scope and Market Segmentation
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Report Metric |
Details |
|
Forecast Period |
2024 to 2031 |
|
Base Year |
2023 |
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Historic Years |
2022 (Customizable to 2016-2021) |
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Quantitative Units |
Revenue in USD Million, Volumes in Units, and Pricing in USD |
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Segments Covered |
Drug Product (AKP-23494954/RQ-00466479, EVT 401, GSK1482160, JNJ-55308942, JNJ-54175446, Others), Application (Central Nervous System Disorders, Immunological Disorders, Others), End User (Hospitals, Ambulatory Surgical Center, Pharmaceutical and Biotechnology Companies, Others) |
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Countries Covered |
U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, U.A.E., Egypt, Israel, Rest of Middle East & Africa |
|
Market Players Covered |
Pfizer (U.S.), Evotec AG (Germany), RaQualia Pharma (Japan), AstraZeneca Plc. (U.K.), GlaxoSmithKline Plc (U.K.), Johnson and Johnson Services, Inc. (U.S.), Asahi Kasei Corporation (Japan) |
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Market Opportunities |
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Market Definition
P2X7 is an ideal drug target as antagonism of P2X7 channel would not cause any severe side effects, as antagonism will only start when high ATP concentrations activate the channel, believed to happen during pathology of neuroinflammatory Antagonism of P2X7 channel does not lead to serious side effects, as antagonism will only start when the channel is activated by high ATP concentrations, believed to happen during pathology of neuroinflammatory disorders of the Central Nervous System (CNS) such as stroke, epilepsy, multiple sclerosis, chronic neurodegenerative, and neuropsychiatric diseases.
Global P2X7 Receptor Antagonists Market Dynamics
Drivers
- Growing prevalence of inflammatory and autoimmune diseases
P2X7 receptors play a role in inflammatory responses, and drugs targeting these receptors are being investigated for their potential in treating inflammatory and autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis.
- Increasing research and development activities
Ongoing research and development efforts in the field of purinergic receptors contribute to the understanding of the therapeutic potential of P2X7 receptor antagonists. As more is discovered about the role of these receptors in various diseases, it may lead to the development of novel drugs.
Opportunities
- Expansion of therapeutic indications
Continued research may uncover new therapeutic indications for P2X7 receptor antagonists. This could lead to the expansion of the market into areas beyond the currently explored conditions, presenting new opportunities for drug development and market growth.
- Pain management innovations
P2X7 receptor antagonists could contribute to innovations in pain management. The development of more effective and targeted analgesic therapies with fewer side effects represents an opportunity in the pharmaceutical market.
Restraints/Challenges
- Complexity of the receptor system
The purinergic receptor system, including P2X7 receptors, is complex and interacts with various pathways. Understanding the full scope of these interactions and developing drugs that selectively target the P2X7 receptor without affecting other related receptors poses a challenge.
- Competition from other therapies
P2X7 receptor antagonists face competition from existing therapies and alternative approaches for treating the same conditions. This competition may limit the market share and adoption of P2X7 receptor antagonist drugs.
This P2X7 receptor antagonists market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, the impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the P2X7 receptor antagonists market contact Data Bridge Market Research for an analyst brief, our team will help you make an informed market decision to achieve market growth.
Recent Developments
- In 2019, AstraZeneca Plc., has also launched another new drug product such as “AZ11657312” is a potent antagonist of the rat P2X7 receptor with a pA2 for inhibition of agonist-stimulated ethidium bromide release of 7.8 (15nM) in HEK cells stating the recombinant rat P2X7 receptor. Treatment of rats with AZ11657312, resulted in a reduction in mechanical hyperalgesia and disease severity in the streptococcal cell wall model of arthritis, and a delay in the adjuvant-induced arthritis model
Global P2X7 Receptor Antagonists Market Scope
The P2X7 Receptor Antagonists market is segmented on the basis of drug product, application and end user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Drug Product
- AKP-23494954/RQ-00466479
- EVT 401
- GSK1482160
- JNJ-55308942
- JNJ-54175446
- Others (e.g.- AZ11657312)
Application
- Central Nervous System Disorders
- Immunological Disorders
- Others
End User
- Hospitals
- Ambulatory surgical center
- Pharmaceutical and biotechnology companies
Global P2X7 Receptor Antagonists Market Regional Analysis/Insights
The P2X7 receptor antagonists market is analyzed and market size insights and trends are provided by country, drug product, application and end user as referenced above.
The countries covered in the P2X7 receptor antagonists market report are U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, rest of Asia-Pacific, Brazil, Argentina, rest of South America, South Africa, Saudi Arabia, U.A.E., Egypt, Israel, and rest of Middle East & Africa.
North America is expected to dominate the market due to the presence of large number of research and development center, availability of FDA approved product, and increasing number of manufacturer.
Asia-Pacific is expected to witness significant growth during the forecast period of 2024 to 2031 due to the increase in government initiatives to promote healthcare, the rising health awareness among the people and growing demand for advanced medical technology for diagnosis and treatment procedures, the large population pool, and the growing demand for quality healthcare in the region.
The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impact the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends, and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, the impact of domestic tariffs, and trade routes are considered while providing forecast analysis of the country data.
Healthcare Infrastructure Growth Installed Base and New Technology Penetration
The P2X7 receptor antagonists market also provides you with a detailed market analysis for every country's growth in healthcare expenditure for capital equipment, installed base of different kinds of products for the P2X7 Receptor Antagonists market, the impact of technology using lifeline curves and changes in healthcare regulatory scenarios and their impact on the P2X7 receptor antagonists market.
Competitive Landscape and P2X7 Receptor Antagonists Market Share Analysis
The P2X7 receptor antagonists market competitive landscape provides details by competitors. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width, and breadth, application dominance. The above data points provided are only related to the companies' focus related to the P2X7 receptor antagonists market.
Some of the major players operating in the P2X7 receptor antagonists market are:
- Pfizer (U.S.)
- Evotec AG (Germany)
- RaQualia Pharma (Japan)
- AstraZeneca Plc. (U.K.)
- GlaxoSmithKline Plc (U.K.)
- Johnson and Johnson Services, Inc. (U.S.)
- Asahi Kasei Corporation (Japan)
SKU-
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Research Methodology
Data collection and base year analysis are done using data collection modules with large sample sizes. The stage includes obtaining market information or related data through various sources and strategies. It includes examining and planning all the data acquired from the past in advance. It likewise envelops the examination of information inconsistencies seen across different information sources. The market data is analysed and estimated using market statistical and coherent models. Also, market share analysis and key trend analysis are the major success factors in the market report. To know more, please request an analyst call or drop down your inquiry.
The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market and primary (industry expert) validation. Data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Patent Analysis, Pricing Analysis, Company Market Share Analysis, Standards of Measurement, Global versus Regional and Vendor Share Analysis. To know more about the research methodology, drop in an inquiry to speak to our industry experts.
Customization Available
Data Bridge Market Research is a leader in advanced formative research. We take pride in servicing our existing and new customers with data and analysis that match and suits their goal. The report can be customized to include price trend analysis of target brands understanding the market for additional countries (ask for the list of countries), clinical trial results data, literature review, refurbished market and product base analysis. Market analysis of target competitors can be analyzed from technology-based analysis to market portfolio strategies. We can add as many competitors that you require data about in the format and data style you are looking for. Our team of analysts can also provide you data in crude raw excel files pivot tables (Fact book) or can assist you in creating presentations from the data sets available in the report.
