Global Whole Genome Bisulfite Sequencing (WGBS) Market, By Product and Service (DNA Extraction, DNA Fragmentation, DNA Repair, Adapter Ligation, Bisulfite Treatment, PCR Amplification), Application (Stem Cell Applications, Developmental Biology, Early Diagnosis of Diseases, Forensic Science), End User (Pharmaceutical and Biotechnology Companies, Academic and Government Institutes, Contract Research Organizations) – Industry Trends and Forecast to 2029.
Whole Genome Bisulfite Sequencing (WGBS) Market Analysis and Size
Whole genome bisulfite sequencing is a next-generation sequencing technology that uses sodium bisulfite to determine the methylation status of single cytosines prior to high-throughput DNA sequencing. The status of DNA methylation at various genes can reveal information about gene regulation and transcriptional activities.
Data Bridge Market Research analyses that the whole genome bisulfite sequencing (WGBS) market which is expected to grow at a healthy CAGR during the forecast period 2022 to 2029. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.
Whole Genome Bisulfite Sequencing (WGBS) Market Scope and Segmentation
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Report Metric |
Details |
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Forecast Period |
2022 to 2029 |
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Base Year |
2021 |
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Historic Years |
2020 (Customizable to 2014 - 2019) |
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Quantitative Units |
Revenue in USD Million, Volumes in Units, Pricing in USD |
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Segments Covered |
Product and Service (DNA Extraction, DNA Fragmentation, DNA Repair, Adapter Ligation, Bisulfite Treatment, PCR Amplification), Application (Stem Cell Applications, Developmental Biology, Early Diagnosis of Diseases, Forensic Science), End User (Pharmaceutical and Biotechnology Companies, Academic and Government Institutes, Contract Research Organizations) |
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Countries Covered |
U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America. |
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Market Players Covered |
Illumina, Inc. (U.S.), Epigentek Group Inc (U.S.), CD Genomics (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Novogene Co., Ltd. (China), PerkinElmer, Inc. (U.S.), Promega Corporation (U.S.), BGI (China), Nebula Genomics (U.S.), Agilent Technologies (U.S.), Qiagen (Germany), Macrogen Inc. (South korea), Oxford Nanopore Technologies plc. (U.K.), Veritas (U.S.) |
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Market Opportunities |
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Market Definition
Whole genome bisulfite sequencing (WGBS) is a critical technique in methylome research. Although a number of tools have been developed to address the mapping challenges caused by bisulfite treatment, the most recent tools available have not been evaluated in terms of read mapping performance as well as biological insights in multiple mammals.
Global Whole Genome Bisulfite Sequencing (WGBS) Market Dynamics
Drivers
- Rise in genome sequencing
Genome sequencing enables genome-wide methylation profiling at the single-base level which provides methylation status of every CpG locus including partial methylation domains, gene deserts, remote regulatory elements, others which reveals methylation sequence background and reveals absolute DNA methylation levels. During the forecast period of 2022–2029, these factors are boosting the growth of the whole genome bisulfite sequencing (WGBS) market.
- Rising applications of whole genome sequencing
Single nucleotide resolution methylation profiling at CG, CHG, and CHH sites. differentially methylated sites linked to experimental treatments or sample conditions, understanding cell differentiation or tissue development mechanisms using methylation profiles and early disease and cancer detection by detecting DNA hypermethylation or hypomethylation. These all are the applications of whole genome sequencing which boost the growth of the market.
Opportunities
- Rising advanced techniques
The increasing number of research and development activities, as well as the adoption of advanced techniques. For instance, whole genome bisulfite sequencing (WGBS) detects methylated cytosines by pre-sequencing the DNA with sodium bisulfite. WGBS has established itself as the gold standard for studying genome-wide methylation at single base resolution. These will provide various opportunities for the growth of the whole genome bisulfite sequencing (WGBS) market during the forecast period.
Restraints/Challenges
- Low coverage of whole genome bisulfite sequencing
The use of whole genome bisulfite sequencing has been hampered primarily by its high cost, complex data output, and low required coverage. Many studies using whole genome bisulfite sequencing assays have few or no biological replicates due to the high amount and subsequent cost of DNA input. Bisulfite converts unmethylated cytosines to thymidines, reducing sequence complexity, which can make it difficult to create alignments.
This whole genome bisulfite sequencing (WGBS) market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the whole genome bisulfite sequencing (WGBS) market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Global Whole Genome Bisulfite Sequencing (WGBS) Market Scope
The whole genome bisulfite sequencing (WGBS) market is segmented on the basis of product and services, application and end user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Product and Service
- DNA Extraction
- DNA Fragmentation
- DNA Repair
- Adapter Ligation
- Bisulfite Treatment
- PCR Amplification
Application
- Stem Cell Applications
- Developmental Biology
- Early Diagnosis of Diseases
- Forensic Science
End User
- Pharmaceutical and Biotechnology Companies
- Academic and Government Institutes
- Contract Research Organizations
Whole Genome Bisulfite Sequencing (WGBS) Market Regional Analysis/Insights
The whole genome bisulfite sequencing (WGBS) market is analysed and market size insights and trends are provided by country, product and services, application and end user as referenced above.
The countries covered in the whole genome bisulfite sequencing (WGBS) market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
North America dominates the whole genome bisulfite sequencing (WGBS) market due to the surging levels of investment for the development of the healthcare industry along with growth of new technologies.
Asia-Pacific is expected to grow at the highest growth rate in the forecast period of 2022 to 2029 owing to the increasing number of population suffering from diabetes.
The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and Whole Genome Bisulfite Sequencing (WGBS) Market Share Analysis
The whole genome bisulfite sequencing (WGBS) market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to whole genome bisulfite sequencing (WGBS) market.
Some of the major players operating in the whole genome bisulfite sequencing (WGBS) market are:
- Illumina, Inc. (U.S.)
- Epigentek Group Inc (U.S.)
- CD Genomics (U.S.)
- Thermo Fisher Scientific, Inc. (U.S.)
- Novogene Co., Ltd. (China)
- PerkinElmer, Inc. (U.S.)
- Promega Corporation (U.S.)
- BGI (China)
- Nebula Genomics (U.S.)
- Agilent Technologies (U.S.)
- Qiagen (Germany)
- Macrogen Inc. (South korea)
- Oxford Nanopore Technologies plc. (U.K.)
- Veritas (U.S.)
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