Oral cancer and head and neck cancer are among the top 10 most prevalent types of cancer. Approximately 250 people in New Zealand are diagnosed with mouth cancer each year. While most instances will be effectively treated, oral cancer must be diagnosed early to increase the chances of success. Early detection is critical since oral cancer therapy can significantly impact someone's life. When patients are diagnosed with oral cancer in its later stages and receive therapy, their daily lives can become extremely challenging since oral cancer treatment affects how they talk, chew, swallow, and engage socially.
VELscope, also known as the VELscope Vx Enhanced Oral Assessment System, is a wireless handheld device that employs natural tissue fluorescence to improve our capacity to detect oral abnormalities that are typically invisible to the human eye. It is frequently utilized as an adjunctive tool for imaging tissue abnormalities in the mouth since it is convenient, easy to use, and employs basic and straightforward technology.
VELscope is a particular type of light to detect abnormalities, effectively used to see early forms of cancer or disease during an oral cancer screening. The VELscope, according to Gabriela Videira, MD of ISCS-Sul and Mário Arajo, RDH, BS, does not detect whether or not an oral lesion is malignant. Instead, the technology just aids in detecting anomalies that are not evident to the human eye.
Data Bridge Market Research analyses that the oral cancer treatment market, USD 1,805.8 million in 2022, would rise to USD 2,729.72 million by 2030 and is expected to undergo a CAGR of 5.30% during the forecast period 2023 to 2030. The oral cancer treatment market is segmented on the basis of type, therapy type, treatment, route of administration, end users, and distribution channel. North America dominates the market in the forecast to the rising affordability of drugs and the surge in the cases of oral cancer. Furthermore, growing awareness among the people in this region to cure dental caries and technological developments due to the presence of major market players lead to market growth.
To learn more about the study, visit: https://www.databridgemarketresearch.com/reports/global-oral-cancer-treatment-market
How Does VELscope Work?
Unlike traditional oral cancer screening, which includes visually inspecting the mouth for red, white, or black spots, VELscope employs a superior blue light to stimulate molecules deep inside the layer of our oral mucosal tissues, such as the mucous membrane lining the interior of the mouth. These energized molecules then emit their own light in green, yellow, and red wavelengths. The VELscope's unique filter enables fluorescence imaging by suppressing reflected blue light and increasing the contrast between normal and diseased tissue. Essentially, VELscope enables dentists to detect dysplastic cells or cells that are just starting to change into pre-cancerous cells via aberrant fluorescence patterns. A variety of factors can contribute to abnormal fluorescence patterns, including:
- Metabolic activity in epithelial tissue has increased
- The fluorescent collagen cross-links in the connective tissue layer underlying the basement membrane were broken down
- An increase in tissue blood content is caused by inflammation or angiogenesis because hemoglobin absorbs fluorescence excitation (blue light) strongly
- Melanin or amalgam particles that absorb light are present.
Oral abnormalities are not visible to the naked eye can now be discovered using VELscope. Furthermore, doctors may now determine the proper margins for surgical excision.
It only takes two or three minutes to complete the VELscope inspection. Every single year, many lives are saved because of this non-invasive, painless surgery. A quick description of a VELscope inspection is provided below:
The dentist will first conduct a standard visual examination of the entire lower face. Along with the teeth, this also refers to the glands, tongue, cheeks, and palate. After that, the mouth is rinsed with a pre-rinse solution for under a minute. The dentist gives patients protective eyewear to safeguard the retinas' structural integrity. To clearly see the oral cavity, the room's lights are decreased.
Oral Cancer and VELscope
The most frequent cause of mouth cancer growth is frequent smoking. Another element that has been linked to a higher risk of mouth cancer is alcohol consumption. On the other side, exposure to the sun may raise your risk of developing lip cancer. You can lower your risk of acquiring mouth cancer by giving up smoking, abstaining from alcohol, using lip balm and sunscreen every day, and quitting drinking.
You naturally have an increased risk of having mouth cancer if you are above forty. Oral cancer risk may also increase as a result of genetic factors. Men are twice as likely as women to have oral cancer. You must go to dental exams and screenings because none of these risk factors are under our control. The most frequent cause of mouth cancer growth is frequent smoking. Alcohol consumption can also raise your risk. Additionally, exposure to the sun may increase your risk of developing lip cancer. You can reduce your chance of mouth cancer by giving up smoking, abstaining from drinking, and using sunscreen.
Since it claims more lives each year than combined testicular, cervical, and brain cancer but receives less attention, oral cancer is frequently referred to as the "forgotten disease." Only 57% of the more than 30,000 Americans who develop oral cancer each year will survive for more than five years without treatment.
Many people think that if they don't use alcohol or tobacco, they won't get mouth cancer. Alcohol and tobacco use does increase the risk of oral cancer, yet 25% of people with the disease abstain from both. Getting annual oral cancer screenings is the greatest method to prevent mouth cancer. Most dentists examine for oral cancer as part of a routine dental examination. The FDA-approved VELscope gives dentists another exam tool to aid in the early detection of oral cancer. The VELscope is a blue excitation lamp that draws attention to alterations in malignant and pre-cancerous cells.
The Velscope System
Let's look at the VELscope itself to understand better how it functions. The VELscope depends on two essential parts: an eyepiece with an inbuilt optical filter and an LED ring that emits a specific wavelength of blue light. Clinicians can see areas that need more research by observing cellular and structural tissue changes while beaming light into the oral cavity and looking at the patient's oral mucosa through an optical filter. We now arrive at the concept of tissue fluorescence.
Tissue Reflectance VS Tissue Fluorescence
Utilizing the principle of tissue reflectance and conventional white light, doctors conduct oral examinations using traditional oral mucosal examination equipment. In contrast, the VELscope uses the idea of tissue fluorescence rather than reflectance. Fluorophores, which are chemical substances that respond to light excitation, are what produce tissue fluorescence. Fluorophores respond to the blue light of the VELscope by generating their own light at a longer wavelength, which can be seen through the VELscope eyepiece's optical filter. The VELscope can see the cellular change in the oral mucosa due to the fluorophores' stimulation, or lack thereof in some cases.
Fluorescence Patterns
The fluorophores in the oral mucosa's tissues normally respond to blue light when observed with the VELscope, as evidenced by the brilliant apple-green color of normal fluorescence patterns. Lymphoid clusters, the fungiform papillae on the tongue, and the extensively vascularized anterior tonsillar pillars are excellent illustrations of how normal fluorescence patterns can also reveal a lack of fluorescence. During a standard white-light reflectance assessment, sick mucosal regions may go unnoticed by the human eye, but abnormal fluorescence patterns enable clinicians to spot them. Normal causes of abnormal fluorescence patterns include:
- An increase in the epithelium's metabolic activity
- Fluorescent collagen cross-links in the connective tissue layer below the basement membrane are broken down
- An increase in tissue blood volume caused by angiogenesis or inflammation (hemoglobin absorbs fluorescence excitation light (blue) and emission light (green) very strongly)
- The presence of light-absorbing pigments, such as melanin or amalgam particles
Although the VELscope is frequently referred to as an instrument for screening for oral cancer, the idea of tissue fluorescence encompasses a wide range of oral abnormalities, enabling the VELscope to assist in visualizing a variety of oral health issues:
- Bacterial, fungi, and viral infections
- Several sources of inflammation, such as lichen planus and other lichenoid reactions
- Trauma
- Squamous papilloma's and salivary gland tumors are examples of oral cancer
- Tooth dysplasia
Data Bridge Market Research analyses that the North America oral care products and other dental consumables market will exhibit a CAGR of around 2.99% for the forecast period of 2021-2028. The growing prevalence of dental disorders, increased focus on research and development proficiencies in regards to medical devices and on the adoption of advanced healthcare technologies, ever-rising geriatric population and rising expenditure on the healthcare infrastructure development especially in the developing economies are the major factors attributable to the growth of oral care products and other dental consumables market. The North America oral care products and other dental consumables market is segmented on the basis of product type and distribution channel.
To learn more about the study, visit: https://www.databridgemarketresearch.com/reports/north-america-oral-care-products-other-dental-consumables-market
Conclusion
벨스코프(VELscope)라는 혁신적인 휴대용 도구는 위생사와 치과의사에게 이상 조직을 조기에 발견할 수 있는 사용하기 쉬운 보조 점막 검사 시스템을 제공합니다. 무해한 청색광이 벨스코프 핸드피스를 통해 구강 내로 방출되어 조직을 자극하여 상피 표면에서부터 기저막(전암성 변화가 일반적으로 시작되는 곳)과 그 아래 기질까지 형광을 발산하게 합니다. 정상 조직은 일반적으로 밝은 사과색을 띠지만, 형광이 부족하면 의심스러운 부위가 구분되어 어둡게 보입니다.
보고와 임상 경험에 따르면, VELscope 기술은 구강 건강 상태를 심층적으로 분석하는 데 유용합니다. 임상가들은 또한 의심스러운 부위를 쉽게 촬영하여 수술적 생검을 실시할 수 있기 때문에 치과 진료에 기술을 접목하는 것이 매우 간단하다고 주장합니다. VELscope는 세계보건기구(WHO) 필수보건기술부로부터 세계적인 보건 문제를 해결하는 혁신적인 의료 기술로 인정받았으며, "저소득 및 중소득 국가에서 사용 가능하고, 적절하며, 저렴할 가능성이 높다"고 평가받았습니다. 이는 VELscope가 비용 효율적이고 사용자 친화적인 방식으로 구강 건강을 개선하는 데 필수적인 도구임을 보여줍니다.
VELscope는 혁신적인 새로운 방법으로 형광 시각화(FV)를 사용합니다. 일반적으로 육안으로는 보이지 않는 이상 부위와 병변을 강렬한 청색광을 입안에 비추어 드러냅니다. 구강암 증상이 경미한 질환의 증상으로 오인될 수 있다는 사실 때문에 구강암 진단은 가장 어려운 과제 중 하나입니다. VELscope 시스템은 치과 의사에게 표면 아래에서 무슨 일이 일어나고 있는지에 대한 귀중한 정보를 제공합니다.
건강한 구강 연조직은 벨스코프(VELscope) 주파수의 청색광을 자연스럽게 흡수합니다. 피부 아래의 건강한 연조직은 녹색으로 변하고, 문제 부위는 훨씬 더 어두워집니다. 벨스코프 시스템을 사용하면 다음과 같은 이점을 얻을 수 있습니다.
- 디지털 사진과의 결합이 가능합니다
- 백색 및 적색 반점, 병변을 감지합니다.
- 백색광에서는 보이지 않는 문제점을 감지합니다.
- 악성 및 전암성 조직을 노출시킵니다.
- FDA 승인
- 치과 의사가 건강에 해로운 연조직이 모두 제거되었는지 확인하는 데 도움이 됩니다.
- 구강암 조기진단을 도와 생존율 향상
- 빠르고 고통 없는 검사
세계 미용 치과 시장은 2021년 234억 5천만 달러 규모였으며, 2029년에는 406억 달러에 도달할 것으로 예상되며, 2022년부터 2029년까지 연평균 성장률 7.10%를 기록할 것으로 예상됩니다. "치과 병원 및 클리닉"은 정부 공인 치과의사를 제공하기 때문에 예측 기간 동안 미용 치과 시장에서 가장 큰 최종 사용자 부문을 차지합니다. 데이터 브리지 마켓 리서치팀이 큐레이팅한 시장 보고서에는 심층 전문가 분석, 환자 역학, 파이프라인 분석, 가격 분석 및 규제 프레임워크가 포함되어 있습니다. 미용 치과 시장은 제품, 연령대 및 최종 사용자를 기준으로 세분화됩니다.
해당 연구에 대한 자세한 내용은 https://www.databridgemarketresearch.com/reports/global-cosmetic-dentistry-market에서 확인하세요.
