Laparoscopic appliers come in a variety of diameters and lengths, allowing them to be used with a variety of clippers. Laparoscopic clip appliers are used in a variety of endoscopic operations, including occluding tiny tissue structures and arteries. In addition, it is employed in radiographic markers. Because of the expanding number of laparoscopic procedures and the increased use of minimally invasive procedures, the market for laparoscopic appliers is expected to develop. Laparoscopy has been demonstrated to treat symptoms more effectively, such as heartburn and regurgitation decrease, and patients reported a higher quality of life than alternative medical treatments, such as proton-pump inhibitor drugs alone.