According to the WHO (World Health Organization), nearly 80% of the world's population lives in cities, and as a result, air quality has a substantial impact on them, mainly in low-income nations. In addition, multiple studies have linked air pollution to allergic rhinitis, asthma, and other disorders, leading to an increase in allergy diagnoses. Although allergies can affect practically every organ in the body and can be triggered by a variety of external causes, there are a few common themes that should be highlighted in research efforts. Effective prevention, curative therapy, and accurate, early diagnosis, as with many other chronic diseases, are key unmet requirements. In order to organize or re-categorize clinical symptoms into more coherent, consistent, and treatment-responsive groupings, detailed phenotyping/endotyping is widely required.
