API intermediates are essential chemical compounds produced during the synthesis of active pharmaceutical ingredients (APIs). These intermediates serve as precursor molecules for the final API and play a crucial role in pharmaceutical manufacturing. The API intermediates market is majorly used in the production of generic pharmaceuticals. Generic drugs, which are identical or bioequivalent versions of brand-name drugs, rely on API intermediates for cost-effective and efficient synthesis. Providing high-quality intermediates, the API intermediates market enables pharmaceutical companies to manufacture affordable alternatives to brand-name medications, thereby enhancing accessibility to essential drugs and promoting competition in the pharmaceutical industry.
Global API Intermediates Market size was valued at USD 2.34 billion in 2022 and is projected to reach USD 5.67 billion by 2030 with a CAGR of 7.10% during the forecast period of 2023-2030.
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Below are the Top API Intermediates Companies with a Significant Market Share:
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Rank
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Company
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Overview
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Product Portfolio
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Sales Geographical Coverage
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Developments
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1.
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Aurobindo Pharma
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Aurobindo Pharma is a leading Indian pharmaceutical company. It is renowned for its diverse portfolio of active pharmaceutical ingredients (APIs) and intermediates. With a strong focus on research and development, it has established itself as a key player in the global API market, supplying high-quality intermediates to various pharmaceutical companies worldwide.
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North America, South America, Asia-Pacific, Europe, and Middle East and Africa
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In January 2021, Aurobindo Pharma received the financial support from the central government under the production-linked incentive (PLI) scheme. The company has received the PLI to promote the domestic production of the KSMs, which are key starting materials, intermediates, and active pharmaceutical ingredients. The government has announced the PLI for the bulk drugs and intermediates so as to reduce the import dependency of the products in the country. This approval and support from the government will help the company to boost up their manufacturing skills and will increase its revenue in the future
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2.
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Divi's Laboratories Limited
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Divi's Laboratories Limited Divi's Labs is a prominent player in the API intermediates market, known for its vertically integrated operations and state-of-the-art manufacturing facilities. Specializing in custom synthesis and process development, the company offers a wide range of intermediates catering to the needs of the pharmaceutical, biotech, and agrochemical industries.
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Europe, U.S., and India
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In 2018, Divi's Laboratories Limited had received certificate of Occupational Health and Safety Management System that is OHSAS 1800:2007. The company has received the certificate from Bureau Veritas Quality International. The company has received the certificate for this category several times which make them outstanding company related to its management system. This certificate has helped the company to get recognition related to the management system of their company
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3.
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BASF SE
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BASF SE As one of the world's largest chemical companies, BASF plays a significant role in the API intermediates market. Leveraging its expertise in chemical synthesis and innovative technologies, BASF supplies a diverse range of high-quality intermediates to pharmaceutical manufacturers globally, contributing to the development of novel drugs and therapies.
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North America, South America, Asia, and Europe
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In June 2017, BASF SE announced that the company is planning to open the plant for the production of ibuprofen in Ludwigshafen, Germany. The production and manufacturing of API ibuprofen will increase the manufacturing of the intermediates of ibuprofen, which will directly improve the intermediate market. Ibuprofen is an anti-inflammatory drug that is used for pain, inflammation, and fever. This plant will be considered as one of the most significant plants of ibuprofen in Germany. This helped the company to become one of the leading companies in production of ibuprofen which will increase the revenues in the field of APIs in the coming future.
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4.
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Cambrex Corporation
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Cambrex Corporation Cambrex is a leading contract development and manufacturing organization (CDMO) specializing in small molecule APIs and intermediates. With a focus on custom synthesis and process optimization, Cambrex provides comprehensive solutions to pharmaceutical companies, ensuring efficient and cost-effective production of intermediates for various drug formulations.
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North America and Europe
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In February 2021, Cambrex Corporation received the CMO Leadership Awards and had received an award for six different categories such as capabilities, compatibility, expertise, quality, reliability, and services. The company has strengthen their position as one of the leading CDMOs that is contract development and manufacturing organization. This recognition helped the company to boost up their manufacturing skills.
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5.
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Sandoz International GmbH
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Sandoz International GmbH As the generic pharmaceutical division of Novartis, Sandoz International is a key player in the API intermediates market. With a global network of manufacturing facilities and a broad portfolio of APIs and intermediates, Sandoz supplies essential components to the pharmaceutical industry, contributing to the accessibility and affordability of generic medications worldwide.
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Americas, Asia-Pacific, Europe, and Middle East, and Africa
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In July 2020, Sandoz International GmbH (a subsidiary of Novartis AG) had announced a joint agreement with Austrian government for long-term production of active ingredients for penicillin products. The company has invested USD 181.57 million for the production of APIs used for penicillin products. The motive of the company was to strengthen the Europe market in terms of antibiotics production as well as introduce the APIs and finished products using innovative technologies. This helped the company enhance its product portfolio in terms of novel technology developed products
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Conclusion
The API intermediates market serves as a foundational pillar in the pharmaceutical industry, facilitating the production of both branded and generic medications. With its role in supplying essential precursor molecules for API synthesis, this market ensures the efficient and cost-effective manufacturing of a wide range of pharmaceutical drugs. Particularly, in the realm of generic pharmaceuticals, API intermediates play a vital role in promoting accessibility to affordable medications and fostering competition within the industry. As pharmaceutical companies continue to innovate and optimize their manufacturing processes, the significance of API intermediates in driving advancements and expanding global healthcare access remains paramount.
